Meciadanol |
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2-(3,4-dihydroxyphenyl)-3-methoxy-3,4-dihydro-2H-chromene-5,7-diol
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Other names
3-O-methylcatechin
Meciadanolum
3',4',5,7-Tetrahydroxy-3-methoxyflavan
(2R,3S)-2-(3,4-Dihydroxyphenyl)-3-methoxy-5,7-chromandiol
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Identifiers |
CAS number |
65350-86-9, 87367-19-9 |
PubChem |
47610 |
Jmol-3D images |
Image 1 |
- COC1CC2=C(C=C(C=C2OC1C3=CC(=C(C=C3)O)O)O)O
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Properties |
Molecular formula |
C16H16O6 |
Molar mass |
304.29 g/mol |
Exact mass |
304.094688 u |
Y (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
Infobox references |
Meciadanol is a synthetic O-methylated flavanol. It is the 3-O-methylation of catechin.
It inhibits the histidine decarboxylase in rats.[1]
References
- ^ Gastric protection by meciadanol. A new synthetic flavonoid-inhibiting histidine decarboxylase. Stanislaw J. Konturek, Mary Ellen Kitler, Tomasz Brzozowski and Tadeusz Radecki, Digestive Diseases and Sciences, Volume 31, Number 8 / 1986, Pages 847-852, doi:10.1007/BF01296054
v · glycosides |
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Flavan-3-ols |
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O-methylated flavan-3ols |
Meciadanol (3-O-methylcatechin)
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Glycosides |
Arthromerin A | Arthromerin B
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Misc. |
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v · d · eHistaminergics |
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Receptor
ligands |
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Agonists: 2-Pyridylethylamine • Betahistine • Histamine • HTMT • UR-AK49
Antagonists: 1st generation: 4-Methyldiphenhydramine • Alimemazine • Antazoline • Azatadine • Bamipine • Benzatropine (Benztropine) • Bepotastine • Bromazine • Brompheniramine • Buclizine • Captodiame • Carbinoxamine • Chlorcyclizine • Chloropyramine • Chlorothen • Chlorphenamine • Chlorphenoxamine • Cinnarizine • Clemastine • Clobenzepam • Clocinizine • Cyclizine • Cyproheptadine • Dacemazine • Deptropine • Dexbrompheniramine • Dexchlorpheniramine • Dimenhydrinate • Dimetindene • Diphenhydramine • Diphenylpyraline • Doxylamine • Embramine • Etybenzatropine (Ethylbenztropine) • Etymemazine • Histapyrrodine • Homochlorcyclizine • Hydroxyethylpromethazine • Hydroxyzine • Isopromethazine • Isothipendyl • Meclozine • Mepyramine (Pyrilamine) • Mequitazine • Methafurylene • Methapyrilene • Methdilazine • Moxastine • Niaprazine • Orphenadrine • Oxatomide • Oxomemazine • Phenindamine • Pheniramine • Phenyltoloxamine • Pimethixene • Piperoxan • Promethazine • Propiomazine • Pyrrobutamine • Talastine • Thenalidine • Thenyldiamine • Thiazinamium • Thonzylamine • Tolpropamine • Tripelennamine • Triprolidine; 2nd generation: Acrivastine • Astemizole • Azelastine • Cetirizine • Clemizole • Clobenztropine • Ebastine • Emedastine • Epinastine • Ketotifen • Latrepirdine • Levocabastine • Loratadine • Mebhydrolin • Mizolastine • Olopatadine • Rupatadine • Setastine • Terfenadine; "3rd generation": Desloratadine • Fexofenadine • Levocetirizine; Miscellaneous: Tricyclic antidepressants ( Amitriptyline, Doxepin, Trimipramine, etc) • Tetracyclic antidepressants ( Mianserin, Mirtazapine, etc) • Serotonin antagonist and reuptake inhibitors ( Trazodone, Nefazodone) • Typical antipsychotics ( Chlorpromazine, Thioridazine, etc) • Atypical antipsychotics ( Clozapine, Olanzapine, Quetiapine, etc)
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Reuptake
inhibitors |
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Enzyme
inhibitors |
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DAO inhibitors
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Aminoguanidine
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Others |
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