Iodophenpropit

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ImageFile=Iodophenpropit.pngImageSize=220px
IUPACName=1- [3-(3H-imidazol-4-yl)propylthio] -N'- [2-(4-iodophenyl)ethyl] formamidine
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Section1=Chembox Identifiers
CASNo=143407-29-8
PubChem=3035746
SMILES=C1=CC(=CC=C1CCN=C(N)SCCCC2=CN=CN2)I
MeSHName=Iodophenpropit
Section2=Chembox Properties
Formula=C₁₅H₁₉IN₄S
MolarMass=414.30763
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Iodophenpropit is a histamine antagonist which binds selectively to the H₃ subtype. Its ¹²⁵I radiolabelled form is used for mapping the distribution of H₃ receptors in the body. [Jansen FP, Wu TS, Voss HP, Steinbusch HW, Vollinga RC, Rademaker B, Bast A, Timmerman H. Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, [125I] -iodophenpropit, to rat brain. "British Journal of Pharmacology". 1994 Oct;113(2):355-62. PMID 7834183] [Jansen FP, Mochizuki T, Maeyama K, Leurs R, Timmerman H. Characterization of histamine H3 receptors in mouse brain using the H3 antagonist [125I] iodophenpropit. "Naunyn Schmiedebergs Archives of Pharmacology". 2000 Jul;362(1):60-7. PMID 10935534]

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