- Cerebellothalamic tract
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Also known as the dentatothalamic tract or the tractus cerebellothalamicus, is part of the superior cerebellar peduncle. It originates in the cerebellar nuclei, crosses completely in the decussation of the brachium conjunctivum, bypasses the red nucleus, and terminates in parts of the ventral anterior nucleus, ventral intermediate, ventral posterolateral nucleus, and central lateral nuclei of the thalamus.
It is mostly separated from the pallidothalamic tracts.[1]
It can play a role in mediating symptoms in hereditary dystonia.[2]
The term "cerebellothalamocortical pathway" is used to indicate termination in the cerebral cortex.[3]
Function
The cerebellothalamic tract transmits information from the cerebellum to the thalamus via neural impulses for the sensory systems.
See also
References
- ^ Gallay MN, Jeanmonod D, Liu J, Morel A (August 2008). "Human pallidothalamic and cerebellothalamic tracts: anatomical basis for functional stereotactic neurosurgery". Brain Struct Funct 212 (6): 443–63. doi:10.1007/s00429-007-0170-0. PMC 2494572. PMID 18193279. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2494572.
- ^ Argyelan M, Carbon M, Niethammer M, et al. (August 2009). "Cerebellothalamocortical connectivity regulates penetrance in dystonia". J. Neurosci. 29 (31): 9740–7. doi:10.1523/JNEUROSCI.2300-09.2009. PMID 19657027. http://www.jneurosci.org/cgi/pmidlookup?view=long&pmid=19657027.
- ^ Molnar GF, Sailer A, Gunraj CA, Lang AE, Lozano AM, Chen R (September 2004). "Thalamic deep brain stimulation activates the cerebellothalamocortical pathway". Neurology 63 (5): 907–9. PMID 15365147.
Human brain, rhombencephalon, metencephalon: cerebellum (TA 14.1.07, GA 9.788) Surface anatomy LobesMedial/lateralVermis: anterior (Central lobule, Culmen, Lingula) · posterior (Folium, Tuber, Uvula) · Vallecula of cerebellum
Hemisphere: anterior (Alar central lobule) · posterior (Biventer lobule, Cerebellar tonsil)Grey matter Molecular layer (Stellate cell, Basket cell)
Purkinje cell layer (Purkinje cell, Bergmann glia cell = Golgi epithelial cell)
Granule cell layer (Golgi cell, Granule cell, Unipolar brush cell)
Fibers: Mossy fibers · Climbing fiber · Parallel fiberWhite matter InternalPedunclesInferior (medulla): Dorsal spinocerebellar tract · Olivocerebellar tract · Cuneocerebellar tract · Juxtarestiform body (Vestibulocerebellar tract)
Middle (pons): Pontocerebellar fibers
Superior (midbrain): Ventral spinocerebellar tract · Dentatothalamic tract · Trigeminocerebellar fibersBrain and spinal cord: neural tracts and fasciculi Sensory/
ascending1°: Pacinian corpuscle/Meissner's corpuscle → Gracile fasciculus/Cuneate fasciculus → Gracile nucleus/Cuneate nucleus
2°: → sensory decussation/arcuate fibers (Posterior external arcuate fibers, Internal arcuate fibers) → Medial lemniscus/Trigeminal lemniscus → Thalamus (VPL, VPM)
3°: → Posterior limb of internal capsule → Postcentral gyrusFast/lateral1° (Free nerve ending → A delta fiber) → 2° (Anterior white commissure → Lateral and Anterior Spinothalamic tract → Spinal lemniscus → VPL of Thalamus) → 3° (Postcentral gyrus) → 4° (Posterior parietal cortex)
2° (Spinotectal tract → Superior colliculus of Midbrain tectum)Slow/medial1° (Group C nerve fiber → Spinoreticular tract → Reticular formation) → 2° (MD of Thalamus) → 3° (Cingulate cortex)Motor/
descendingPyramidalflexion: Primary motor cortex → Genu of internal capsule → Corticobulbar tract → Facial motor nucleus → Facial muscles
flexion: Red nucleus → Rubrospinal tract
extension: Vestibulocerebellum → Vestibular nuclei → Vestibulospinal tract
extension: Vestibulocerebellum → Reticular formation → Reticulospinal tract
Midbrain tectum → Tectospinal tract → muscles of neckdirect: 1° (Motor cortex → Striatum) → 2° (GPi) → 3° (Lenticular fasciculus/Ansa lenticularis → Thalamic fasciculus → VL of Thalamus) → 4° (Thalamocortical radiations → Supplementary motor area) → 5° (Motor cortex)
indirect: 1° (Motor cortex → Striatum) → 2° (GPe) → 3° (Subthalamic fasciculus → Subthalamic nucleus) → 4° (Subthalamic fasciculus → GPi) → 5° (Lenticular fasciculus/Ansa lenticularis → Thalamic fasciculus → VL of Thalamus) → 6° (Thalamocortical radiations → Supplementary motor area) → 7° (Motor cortex)
nigrostriatal pathway: Pars compacta → StriatumCerebellar AfferentVestibular nucleus → Vestibulocerebellar tract → ICP → Cerebellum → Granule cell
Pontine nuclei → Pontocerebellar fibers → MCP → Deep cerebellar nuclei → Granule cell
Inferior olivary nucleus → Olivocerebellar tract → ICP → Hemisphere → Purkinje cell → Deep cerebellar nucleiEfferentDentate nucleus in Lateral hemisphere/pontocerebellum → SCP → Dentatothalamic tract → Thalamus (VL) → Motor cortex
Interposed nucleus in Intermediate hemisphere/spinocerebellum → SCP → Reticular formation, or → Cerebellothalamic tract → Red nucleus → Thalamus (VL) → Motor cortex
Fastigial nucleus in Flocculonodular lobe/vestibulocerebellum → Vestibulocerebellar tract → Vestibular nucleusBidirectional:
SpinocerebellarUnc. prop.lower limb → 1° (muscle spindles → DRG) → 2° (Posterior thoracic nucleus → Dorsal/posterior spinocerebellar tract → ICP → Cerebellar vermis)
upper limb → 1° (muscle spindles → DRG) → 2° (Accessory cuneate nucleus → Cuneocerebellar tract → ICP → Anterior lobe of cerebellum)lower limb → 1° (Golgi tendon organ) → 2° (Ventral/anterior spinocerebellar tract→ SCP → Cerebellar vermis)
upper limb → 1° (Golgi tendon organ) → 2° (Rostral spinocerebellar tract → ICP → Cerebellum)Categories:- Nervous system
- Neuroanatomy stubs
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