- Cuneate nucleus
Brain: Cuneate nucleus Dissection of brain-stem. Dorsal view. (Label for "nucleus cuneatus" is on left, third from the bottom.) Section of the medulla oblongata at about the middle of the olive. Latin nucleus cuneatus Gray's subject #187 774 NeuroNames hier-764 NeuroLex ID birnlex_2640
One of the dorsal column nuclei, the cuneate nucleus is a wedge-shaped nucleus in the closed part of the medulla oblongata. It contains cells that give rise to the cuneate tubercle, visible on the posterior aspect of the medulla. It lies laterally to the gracile nucleus and medial to the spinal trigeminal nucleus in the medulla.
The cuneate nucleus is part of dorsal column-medial lemniscus system, carrying fine touch and proprioceptive information from the upper body (above T6, except the face and ear - the information from the face and ear is carried by the primary sensory trigeminal nucleus) to the contralateral thalamus via the medial lemniscus.
It receives direct input from the mechanoreceptors of the upper body as well as indirect input from them via the spinal cord. It is also subject to descending control from the central nervous system.
Human brain: rhombencephalon, myelencephalon: medulla (TA A14.1.04, GA 9.767) DorsalSurfaceGrey: otherWhite: Sensory/ascendingWhite: Motor/descending VentralWhite: Motor/descendingSurface Grey: Raphe/
Brain and spinal cord: neural tracts and fasciculi Sensory/
ascending3°: → Posterior limb of internal capsule → Postcentral gyrusFast/lateralSlow/medial
descendingPyramidalMidbrain tectum → Tectospinal tract → muscles of neck
direct: 1° (Motor cortex → Striatum) → 2° (GPi) → 3° (Lenticular fasciculus/Ansa lenticularis → Thalamic fasciculus → VL of Thalamus) → 4° (Thalamocortical radiations → Supplementary motor area) → 5° (Motor cortex)
indirect: 1° (Motor cortex → Striatum) → 2° (GPe) → 3° (Subthalamic fasciculus → Subthalamic nucleus) → 4° (Subthalamic fasciculus → GPi) → 5° (Lenticular fasciculus/Ansa lenticularis → Thalamic fasciculus → VL of Thalamus) → 6° (Thalamocortical radiations → Supplementary motor area) → 7° (Motor cortex)nigrostriatal pathway: Pars compacta → Striatum
CerebellarAfferentEfferentFastigial nucleus in Flocculonodular lobe/vestibulocerebellum → Vestibulocerebellar tract → Vestibular nucleusBidirectional:
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