Nucleus raphe obscurus

Nucleus raphe obscurus
Brain: Nucleus raphe obscurus
Gray694.png
Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but 'raphe' labeled at left.)
Latin nucleus raphes obscurus
NeuroNames hier-737
NeuroLex ID birnlex_1362

The nucleus raphes obscurus, despite the implications of its name, has some very specific functions and connections of afferent and efferent nature. The nucleus raphes obscurus projects to the cerebellar lobes VI and VII and to crus II along with the nucleus raphes pontis [1].

This so called nucleus raphes obscurus has also been implicated in the modulation of the hypoglossal nerve. It has been observed that the ablation of this nucleus causes a change in the firing pattern in the XII nerve [2].

In addition, the nucleus raphes obscurus mediates expiration via the effect of serotonin and depresses periodic synaptic potentials [3]. It has also been shown that this nucleus stimulates gastrointestinal motor function; microinjections of 5-HT into the nucleus raphes obscurus increase gastric movement [4].

See also

References

  1. ^ Brodal, A. Neurological Anatomy in relation to Clinical Medication 3rd ed. Oxford Press. 1981
  2. ^ Peever JH, Necakov A, Duffin J., "Nucleus raphe obscurus modulates hypoglossal output of neonatal rat in vitro transverse brain stem slices." Journal of Appl Physiol. 2001 Jan;90(1):269-79
  3. ^ Lalley PM, Benacka R, Bischoff AM, Richter DW, "Nucleus raphe obscurus evokes 5-HT-1A receptor-mediated modulation of respiratory neurons". Brain Research Volume 747, Issue 1 , 30 January 1997, Pages 156-159
  4. ^ Krowicki, ZK and Hornby, PJ. "Serotonin microinjected into the nucleus raphe obscurus increases intragastric pressure in the rat via a vagally mediated pathway", Pharmacology and Experimental Therapeutics. Volume 265, Issue 1, pp. 468-476, 04/01/1993

Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Nucleus raphe magnus — Brain: Nucleus raphe magnus Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but raphe labeled at left.) Latin nucleus raphes magnus NeuroNames …   Wikipedia

  • Nucleus raphe pallidus — Brain: Nucleus raphe pallidus Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but raphe labeled at left.) Latin nucleus raphes pallidus NeuroNames …   Wikipedia

  • nucleus raphes obscurus — [TA] obscurus raphe nucleus: a raphe nucleus of the medulla oblongata closely associated with the nucleus pallidus raphes; its neurons are serotoninergic …   Medical dictionary

  • Raphe nuclei — Infobox Brain Name = PAGENAME Latin = nuclei raphes GraySubject = GrayPage = Caption = Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but raphe labeled at left.) Caption2 = IsPartOf = Components =… …   Wikipedia

  • nucleus raphes pallidus — [TA] pallidal raphe nucleus: a raphe nucleus of the medulla oblongata closely associated with the nucleus raphes obscurus; its neurons are serotoninergic …   Medical dictionary

  • raphe nuclei — nuclei raphes [TA] the median column reticular nuclei, a subgroup of the reticular nuclei of the brainstem, found in narrow longitudinal sheets along the raphae of the medulla oblongata, pons, and mesencephalon; they include many neurons that… …   Medical dictionary

  • Nucleus — 1) In cell biology, the structure that houses the chromosomes. 2) In neuroanatomy, a group of nerve cells. * * * 1. In cytology, typically a rounded or oval mass of protoplasm within the cytoplasm of a plant or animal cell; it is surrounded by a… …   Medical dictionary

  • Nucleus ambiguus — Brain: Nucleus ambiguus Transverse section of medulla oblongata below the middle of the olive. ( Nucleus ambiguus labeled at center right.) Gray s subject #187 …   Wikipedia

  • Nucleus prepositus hypoglossi — Located in the medulla, the nucleus prepositus hypoglossi or NPH is part of the horizontal gaze holding system. It functions as a neural integrator. A cross section of the lower pons showing the nucleus prepositus hypoglossi (#5) labeled at the… …   Wikipedia

  • nucleus raphes magnus — [TA] magnus raphe nucleus: a raphe nucleus partially overlapping the nucleus pallidus and nucleus obscurus in the medulla oblongata and projecting upward into the caudal pons; its neurons are serotoninergic …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”