Felypressin Identifiers CAS number PubChem ChemSpider UNII DrugBank ChEBI ChEMBL Jmol-3D images Image 1 Properties Molecular formula C46H65N13O11S2 Molar mass 1040.22 g/mol (what is: /?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Felypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. It is added to some local anaesthetics such as prilocaine in a concentration of 0.03 IU/ml. Felypressin is a Vasopressin 1 agonist, and will thus have affects at all Arginine vasopressin receptor 1As. It will, however, have its main physiological effects on vascular SMC's due to the form in which it is administered.
V1 receptors are found in various sites around the body. The major points include the CNS, Liver, Anterior Pituitary, Muscle (both vascular and non-vascular smooth muscle), and Platelets (CLAMP).
Another example of a V1 agonist is terlipressin - which is used in oesophageal varices.
- "Vasopressin analogues and treatments", Prof Buckingham, Imperial College School of Medicine (ICSM) - adapted by JHPatel
Hypothalamic-pituitary hormones and analogues (H01) Hypothalamic Anterior pituitaryAgonists: Thyrotropin Posterior pituitary Neuropeptidergics Cholecystokinin CRHAgonists: Corticotropin releasing hormone GalaninAgonists: Galanin • Galanin-like peptide • Galmic • GalnonAgonists: Galanin • Galanin-like peptide • Galmic • GalnonAgonists: Galanin • Galmic • Galnon Ghrelin MCHAgonists: Melanin concentrating hormone MelanocortinAgonists: alpha-MSH • Melanotan II Neuropeptide SAgonists: Neuropeptide S
Neuropeptide Y Neurotensin Opioidsee Template:Opioids Orexin Oxytocin TachykininAgonists: Substance P
Antagonists: Aprepitant • Befetupitant • Casopitant • CI-1021 • CP-96,345 • CP-99,994 • CP-122,721 • Dapitant • Ezlopitant • FK-888 • Fosaprepitant • GR-203,040 • GW-597,599 • HSP-117 • L-733,060 • L-741,671 • L-743,310 • L-758,298 • Lanepitant • LY-306,740 • Maropitant • Netupitant • NKP-608 • Nolpitantium • Orvepitant • RP-67,580 • SDZ NKT 343 • Vestipitant • Vofopitant
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