- Mecasermin
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Mecasermin Clinical data AHFS/Drugs.com monograph Pregnancy cat. C(US) Legal status ℞-only (US) Routes Subcutaneous Identifiers ATC code H01AC03 UNII 7GR9I2683O KEGG D04870 ChEMBL CHEMBL1201716 Chemical data Formula ? (what is this?) (verify) Mecasermin (INN, brand name Increlex) is recombinant human insulin-like growth factor 1 (IGF-I) which is used for the long-term treatment of growth failure in children with severe primary IGF-I deficiency.[1][2]
This drug is not to be confused with mecasermin rinfabate (trade name: Iplex), which is the binary complex of recombinant human IGF-1 (rhIGF-1) and the binding protein that IGF-1 is naturally adhered to in the human body.
References
- ^ Fintini, D; Brufani, C; Cappa, M (2009). "Profile of mecasermin for the long-term treatment of growth failure in children and adolescents with severe primary IGF-1 deficiency". Therapeutics and clinical risk management 5 (3): 553–9. PMC 2724186. PMID 19707272. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2724186.
- ^ "Increlex". Drugs.com. http://www.drugs.com/increlex.html. Retrieved 10 January 2010.
Hypothalamic-pituitary hormones and analogues (H01) Hypothalamic Agonists: Lanreotide • OctreotideAnterior pituitary Agonists: Corticotropin • Cosyntropin • TetracosactideAgonists: ThyrotropinPosterior pituitary Agonists: Argipressin • Desmopressin • Felypressin • Lypressin • Ornipressin • Terlipressin
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