Oxacephem

Oxacephem
Latamoxef or moxalactam

An oxacephem is a molecule similar to a cephem, but with oxygen substituted for the sulfur. They are synthetically made compounds and have not been discovered in nature.

An example is moxalactam.[1]

Another example is flomoxef.[2][3]

References

  1. ^ "Medscape.com". http://www.medscape.com/viewarticle/464632_2. Retrieved 2008-12-29. 
  2. ^ Yazawa K, Mikami Y, Uno J, Otozai K, Arai T (December 1989). "In-vitro activity of flomoxef, a new oxacephem group antibiotic, against Nocardia in comparison with other cephalosporins". J. Antimicrob. Chemother. 24 (6): 921–5. doi:10.1093/jac/24.6.921. PMID 2621177. http://jac.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=2621177. 
  3. ^ Cazzola M, Brancaccio V, De Giglio C, Paternò E, Matera MG, Rossi F (March 1993). "Flomoxef, a new oxacephem antibiotic, does not cause hemostatic defects". Int J Clin Pharmacol Ther Toxicol 31 (3): 148–52. PMID 8468113.