- Carboxypenicillin
The carboxypenicillins are a group of
antibiotic s. They belong to thepenicillin family and comprise the memberscarbenicillin andticarcillin .Chemical structure
The carboxypenicillins feature the
beta-lactam backbone of all penicillins but also feature acarboxylic acid or carboxylic acid ester group in the variable side-chain.Spectrum
The carboxypenicillins exhibit activity against
gram negative organisms including "Pseudomonas aeruginosa " and "Proteus" species. They are inactive against certaingram positive pathogens such as "Staphylococcus aureus ", "Enterococcus faecalis ", and "L. monocytogenes ". The carboxypenicillins arebeta-lactamase sensitive.
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