Clavam

Clavam
clavulanic acid

A clavam is a molecule similar to a penam, but with an oxygen substituted for the sulfur.[1] Thus, they are also known as oxapenams.

An example is clavulanic acid.[2]

References

  1. ^ "Medscape.com". http://www.medscape.com/viewarticle/464632_2. Retrieved 2008-12-29. 
  2. ^ Chemical Research Laboratory, Oxford University (The Schofield Group). "Antibiotic Biosynthesis, Clavulanic Acid Mode of Action and Biosynthesis". http://www.chem.ox.ac.uk/oc/cjschofield/biosynthesis.htm. Retrieved 2011-7-25. 
v · d · eAntibacterials: cell envelope antibiotics (J01C-J01D)
Intracellular
inhibit peptidoglycan subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin) • DADAL/AR inhibitors (Cycloserine) • bactoprenol inhibitors (Bacitracin)
Glycopeptide
inhibit PG chain elongation: Vancomycin# (Oritavancin, Telavancin) • Teicoplanin (Dalbavancin) • Ramoplanin
β-lactams/
(inhibit PBP
cross-links)
Penicillins/
(penams)

Benzylpenicillin (G)#: Clometocillin • Benzathine benzylpenicillin#  • Procaine benzylpenicillin# • Azidocillin • Penamecillin

Phenoxymethylpenicillin (V)#: Propicillin • Benzathine phenoxymethylpenicillin • Pheneticillin
Penems
Biapenem • Ertapenem • antipseudomonal (Doripenem • Imipenem • Meropenem) • Panipenem
4th (antips-)
Ceftobiprole • Ceftaroline fosamil
Aztreonam • Tigemonam • Carumonam • Tabtoxin
penam (Sulbactam, Tazobactam) • clavam (Clavulanic acid)
Combinations
Other
polymyxins/detergent (Colistin, Polymyxin B) • depolarizing (Daptomycin) • hydrolyze NAM-NAG (Lysozyme) • Gramicidin
#WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III

M: BAC

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)

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Look at other dictionaries:

  • clavam — noun A molecule similar to a penam, but with an oxygen atom substituted for sulfur, such as clavulanic acid …   Wiktionary

  • Clavam — Cla|vam [Kurzw. aus Clavulansäure u. ↑ Lactam], das; s, e: ↑ Clavulansäure …   Universal-Lexikon

  • Clavulanic acid — Systematic (IUPAC) name …   Wikipedia

  • CLAVA — ramus ex utraque parte praecisus, et sic pro fuste et baculo est; ex Graeco κλάδα, quod idem cum κλάδος, ramus, apud Hesych. unde κλάβαν Aeoles fecêre, Latini Clavam. Hinc Clavam Herculis, ramum etiam vocant Latmi Poetae. Propert. Ille etiam Eleo …   Hofmann J. Lexicon universale

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  • Meticillin — Systematic (IUPAC) name (2S,5R,6R) 6 [(2,6 dimethoxybenzoyl)amino] 3,3 dimethyl 7 oxo 4 thia 1 azabicyclo[3.2.0]heptane 2 carboxylic acid Clinical data …   Wikipedia

  • Lysozyme — single crystal Identifiers EC number 3.2.1.17 …   Wikipedia

  • Isoniazid — Systematic (IUPAC) name isonicotinohydrazide …   Wikipedia

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