Bacampicillin

Drugbox
IUPAC_name = 1-Ethoxycarbonyloxyethyl (2"S",5"R")-6- [(2"R")-2-amino-2-phenylacetyl] amino] -3,3-dimethyl-7-oxo-4-thia-1-azabicyclo [3.2.0] heptane-2-carboxylate

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CAS_number = 37661-08-8
CAS_supplemental =
ATC_prefix = J01
ATC_suffix = CA06
ATC_supplemental =
PubChem = 39849
DrugBank =
chemical_formula =
C=21 | H=27 | N=3 | O=7 | S=1
molecular_weight = 465.519 g/mol
bioavailability =
protein_bound =
metabolism = Rapidly hydrolyzed to ampicillin
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category=
legal_AU =
legal_CA =
legal_UK =
legal_US =
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routes_of_administration = Oral

Bacampicillin (INN) is a penicillin antibiotic. It is a prodrug of ampicillin with improved oral bioavailability. [cite journal |author=Bodin NO, Ekström B, Forsgren U, "et al" |title=Bacampicillin: a new orally well-absorbed derivative of ampicillin |journal=Antimicrob Agents Chemother |volume=8 |issue=5 |pages=518–25 |year=1975 |month=November |pmid=1211909 |doi= |url=http://aac.asm.org/cgi/pmidlookup?view=long&pmid=1211909]

It is sold under the brand names Spectrobid (Pfizer) and Penglobe (AstraZeneca).

References