Codeinone

Codeinone
IUPAC name (5α)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-one
Identifiers
CAS number	467-13-0 N
PubChem	5459910
ChemSpider	4573639 Y
ChEBI	CHEBI:18399 Y
ChEMBL	CHEMBL257627 Y
Jmol-3D images	Image 1
SMILES O=C1\C=C/[C@H]5[C@@H]4N(CC[C@@]52c3c(O[C@@H]12)c(OC)ccc3C4)C
InChI InChI=1S/C18H19NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-12,17H,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1 Y Key: XYYVYLMBEZUESM-CMKMFDCUSA-N Y InChI=1/C18H19NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-12,17H,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1 Key: XYYVYLMBEZUESM-CMKMFDCUBF
Properties
Molecular formula	C18H19NO3
Molar mass	297.35 g mol−1
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Codeinone is 1/3 as active as codeine as an analgesic but it is an important intermediate in the production of hydrocodone, a painkiller about 3/4 the potency of morphine.^{[citation needed]}

Chemical structure

Codeinone can described as the methylether of morphinone: 3-methyl-morphinone.

Codeinone can be also described as the ketone of codeine: codein-6-on.

References

This analgesic-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Morphinans Phenol ethers Ethers Ketones Mu-opioid agonists Semisynthetic opioids Analgesic stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно сделать НИР? Compass Group Royal College of Science and Technology Look at other dictionaries: Codeinone reductase (NADPH) — Identifiers EC number 1.1.1.247 CAS number 153302 41 1 …   Wikipedia codeinone — noun A particular narcotic painkiller …   Wiktionary Opioid — Endogenous opioid peptides Skeletal molecular images Adrenorphin Amidorphin Casomorphin …   Wikipedia Oxycodone — Structure de l oxycodone Général Nom IUPAC 4,5 α époxy 14 hydroxy 3 méthoxy 17 méthyl morphinan 6 one …   Wikipédia en Français 76-42-6 — Oxycodone Oxycodone Structure de l oxycodone Général Nom IUPAC 4,5 α époxy 14 hydroxy 3 méthoxy 17 méthyl morphinan 6 one …   Wikipédia en Français Alfentanil — Général Nom IUPAC N [1 [2 (4 éthyl 5 oxo 1,4 dihydrotétrazol 1 yl)éthyl] 4 (méthoxyméthyl) 4 pipéridyl] N phényl propanamide …   Wikipédia en Français Buprénorphine — Structure de la buprénorphine Général Nom IUPAC (2S) 2 [(–) (5R, 6R, 7R, 14S) 9a cyclopropylméthyl 4,5 époxy 3 hydroxy 6 métho …   Wikipédia en Français C18H21NO — Oxycodone Oxycodone Structure de l oxycodone Général Nom IUPAC 4,5 α époxy 14 hydroxy 3 méthoxy 17 méthyl morphinan 6 one …   Wikipédia en Français C18H21NO4 — Oxycodone Oxycodone Structure de l oxycodone Général Nom IUPAC 4,5 α époxy 14 hydroxy 3 méthoxy 17 méthyl morphinan 6 one …   Wikipédia en Français Codéine — Général Nom IUPAC (5R,6S) 7,8 didehydro 4,5 époxy 3 méthoxy N méthylmorphinan 6 ol No CA …   Wikipédia en Français 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”