Anisindione

Anisindione
Anisindione
Systematic (IUPAC) name
2-(4-methoxyphenyl)indene-1,3-dione
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
Pregnancy cat.  ?
Legal status  ?
Routes Oral
Identifiers
CAS number 117-37-3 YesY
ATC code None
PubChem CID 2197
DrugBank APRD00799
ChemSpider 2112 YesY
UNII S747T1ERAJ YesY
KEGG D07457 YesY
ChEBI CHEBI:133809 YesY
ChEMBL CHEMBL712 YesY
Chemical data
Formula C16H12O3 
Mol. mass 252.265 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Anisindione (brand name Miradon) is a synthetic anticoagulant and an indanedione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K–mediated gamma-carboxylation of precursor proteins.

v · d · eAntithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)
Antiplatelet drugs
Thromboxane inhibitors
thromboxane synthase inhibitors (Dipyridamole, Picotamide) • receptor antagonist (Terutroban†)
Other
Anticoagulants
Vitamin K antagonists
(inhibit II, VII, IX, X)
Factor Xa inhibitors
(with some II inhibition)

low-molecular-weight heparin (Bemiparin, Certoparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin)

oligosaccharides (Fondaparinux, Idraparinux)

heparinoid (Danaparoid, Sulodexide, Dermatan sulfate)
xabans (Apixaban, Betrixaban, Edoxaban, Otamixaban, Rivaroxaban)

bivalent: Hirudin (Bivalirudin, Lepirudin, Desirudin)

univalent: Argatroban • Dabigatran • Melagatran‡ • Ximelagatran‡
Other
Thrombolytic drugs/
fibrinolytics
Non-medicinal
Citrate • EDTA • Oxalate

M: MYL

cell/phys (coag, heme, immu, gran), csfs

rbmg/mogr/tumr/hist, sysi/epon, btst

drug (B1/2/3+5+6), btst, trns


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