Phenindione

Phenindione

Systematic (IUPAC) name
2-phenyl-1H-indene-1,3(2H)-dione
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	D(AU) Passes into breast milk
Legal status	?
Routes	Oral
Pharmacokinetic data
Protein binding	88%
Half-life	5 to 10 hours
Identifiers
CAS number	83-12-5 Y
ATC code	B01AA02
PubChem	CID 4760
DrugBank	APRD00166
ChemSpider	4596 Y
UNII	5M7Y6274ZE Y
KEGG	D08354 Y
ChEBI	CHEBI:8066 N
ChEMBL	CHEMBL711 Y
Chemical data
Formula	C15H10O2
Mol. mass	222.239 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H Y Key:NFBAXHOPROOJAW-UHFFFAOYSA-N Y
N(what is this?)  (verify)

Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

Hypersensitivity has been observed.^[1]

References

1. ^ Naisbitt DJ, Farrell J, Chamberlain PJ et al. (June 2005). "Characterization of the T-cell response in a patient with phenindione hypersensitivity". J. Pharmacol. Exp. Ther. 313 (3): 1058–65. doi:10.1124/jpet.105.083758. PMID 15743920. http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=15743920. 

External links

• DDB 30536

This drug article relating to the blood and blood forming organs is a stub. You can help Wikipedia by expanding it.v · Categories: Vitamin K antagonists Indanes Ketones Blood and blood forming organ drug stubs Wikimedia Foundation. 2010. Игры ⚽ Нужен реферат? Maryland Route 158 Companion Piece Look at other dictionaries: Phénindione — Général Nom IUPAC 2 phényl 1H indène 1,3(2H) dione No CAS …   Wikipédia en Français phénindione — ● phénindione nom masculin Médicament anticoagulant d action rapide. (C est une antivitamine K utilisée pour la prévention et le traitement des thromboses et embolies.) …   Encyclopédie Universelle phenindione — 2 Phenyl 1,3 indanedione: a synthetic anticoagulant with action and uses similar to those of bishydroxycoumarin. SYN: phenylindanedione. * * * phen·in·di·one .fen in dī .ōn n an anticoagulant drug C15H10O2 * * * n. an anticoagulant drug use …   Medical dictionary phenindione — n. an anticoagulant drug administered by mouth to prevent or treat thrombosis in the blood vessels of the heart and limbs. The main adverse effect is bleeding (see warfarin); other side effects may include rashes and other allergic reactions …   The new mediacal dictionary phenindione — …   Useful english dictionary Anticoagulant — An anticoagulant is a substance that prevents coagulation (clotting) of blood. A group of pharmaceuticals called anticoagulants can be used in vivo as a medication for thrombotic disorders. Some anticoagulants are used in medical equipment, such… …   Wikipedia Clorindione — Systematic (IUPAC) name 2 (4 chlorophenyl) 1H indene 1,3(2H) dione Clinical data Pregnancy cat.  ? …   Wikipedia phenylindanedione — SYN: phenindione. * * * phen·yl·in·dane·di·one (fen″əl in dānґde ōn) phenindione …   Medical dictionary Antagoniste de la vitamine K — Vitamine K2 (ménaquinone). Dans la ménaquinone, la chaîne latérale est constituée d un nombre variable d unités isoprénoïdes. Les anti vitamine K ou AVK (en anglais VKA Vitamin K antagonist) forment un classe d anticoagulants. Ils réduisent la… …   Wikipédia en Français Aspirin — Asprin redirects here. For the author, see Robert Asprin. Aspirin …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”