Anistreplase

Anistreplase

drugbox
IUPAC_name =


CAS_number = 81669-57-0
ATC_prefix = B01
ATC_suffix = AD03
ATC_supplemental =
PubChem =
DrugBank = BTD00102
C=2569 | H=3928 | N=746 | O=781 | S=40
molecular_weight = 59042.3 g/mol
bioavailability =
protein_bound =
metabolism =
elimination_half-life = 90 minutes
pregnancy_category =
legal_status =
routes_of_administration =

Anistreplase is a thrombolytic drug.cite journal |author=Rawles J |title=Magnitude of benefit from earlier thrombolytic treatment in acute myocardial infarction: new evidence from Grampian region early anistreplase trial (GREAT) |journal=BMJ |volume=312 |issue=7025 |pages=212–5 |year=1996 |month=January |pmid=8563585 |pmc=2350007 |doi= |url=http://bmj.com/cgi/pmidlookup?view=long&pmid=8563585] It converts plasminogen to plasmin, which in turn degrades fibrin (blood clots) to fibrin split products.

Also known as anisoylated plasminogen streptokinase activator complex (APSAC)

References


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Look at other dictionaries:

  • anistreplase — an·i·strep·lase .an i strep (.)lās, .an (.)ī ; a nis trə .plās n a thrombolytic complex of plasminogen and streptokinase used esp. to treat heart attack and to lyse thrombi in coronary arteries called also APSAC * * * an·is·trep·lase (an is… …   Medical dictionary

  • Анистреплаза (Anistreplase) — фибринолитический лекарственный препарат, в состав которого входит комплекс из стрептокиназы и плазминогена. Назначается в инъекциях для лечения ко ронарного тромбоза. Возможные побочные эффекты: локальное кровотечение, замедление сердцебиения,… …   Медицинские термины

  • AFTER — Anistreplase Following Thrombolysis Effect on Reocclusion [study]; Aspirin/Anticoagulants Following Thrombolysis with Eminase in Recurrent Infarction [study]; Aspirin/Anticoagulants Following Thrombolysis with Eminase Results [study] …   Medical dictionary

  • АНИСТРЕПЛАЗА — (anistreplase) фибринолитический лекарственный препарат, в состав которого входит комплекс из стрептокиназы и плазминогена. Назначается в инъекциях для лечения ко ронарного тромбоза. Возможные побочные эффекты: локальное кровотечение, замедление… …   Толковый словарь по медицине

  • AFTER — • Anistreplase Following Thrombolysis Effect on Reocclusion [study]; • Aspirin/Anticoagulants Following Thrombolysis with Eminase in Recurrent Infarction [study]; • Aspirin/Anticoagulants Following Thrombolysis with Eminase Results [study] …   Dictionary of medical acronyms & abbreviations

  • Clopidogrel — Systematic (IUPAC) name (+) (S) methyl 2 …   Wikipedia

  • Thrombolytic drug — Thrombolytic drugs are used in medicine to dissolve blood clots in a procedure termed thrombolysis. They limit the damage caused by the blockage of the blood vessel. Contents 1 Uses 2 Members 3 Side effects …   Wikipedia

  • International Studies of Infarct Survival — The International Studies of Infarct Survival (ISIS) were four randomized controlled trials of several drugs for treating suspected acute myocardial infarction ( heart attack ). More than 134,000 patients from over 20 countries took part in four… …   Wikipedia

  • Eminase — Em·i·nase em i .nās, .nāz trademark used for a preparation of anistreplase * * * Em·in·ase (emґin ās) trademark for preparations of anistreplase …   Medical dictionary

  • Aspirin — Asprin redirects here. For the author, see Robert Asprin. Aspirin …   Wikipedia

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