Lepirudin

Lepirudin

drugbox
IUPAC_name =


CAS_number = 120993-53-5
ATC_prefix = B01
ATC_suffix = AE02
ATC_supplemental =
PubChem =
DrugBank = BTD00024
C=288 | H=448 | N=80 | O=110 | S=6
molecular_weight = 6983.5 g/mol
bioavailability = 100%
protein_bound =
metabolism =
elimination_half-life = ~1.3 hours
excretion = Renal
pregnancy_AU =
pregnancy_US = B
pregnancy_category =
legal_AU =
legal_UK =
legal_US =
legal_status =
routes_of_administration = SQ or IV

Lepirudin (Refludan ) is an anticoagulant which functions as a direct thrombin inhibitor.

It is derived from the saliva of the medicinal leech "Hirudo medicinalis".

Lepirudin may be used as a medication in Heparin-induced thrombocytopenia.

External links

* [http://www.leechesturkey.com Hirudo Medicinalis TURKEY, Supplier of Hirudo Medicinalis]
* [http://www.tibbisuluk.com Hirudo Medicinalis TURKEY,
*
*
*
*
* http://www.refludan.com/product/index.htm


Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • Lepirudin — Hirudin 1 (Hirudo medicinalis), Lepirudin Modell von Hirudin (Stäbchen) im Komplex mit …   Deutsch Wikipedia

  • lepirudin — lep·i·ru·din (lep″ĭ rooґdin) a type of direct thrombin inhibitor that is a recombinant form of hirudin, used as an anticoagulant in patients with heparin induced thrombocytopenia and associated thromboembolic disease; administered… …   Medical dictionary

  • lepirudin — A drug that inhibits blood clotting. It is being studied in cancer treatment …   English dictionary of cancer terms

  • Hirudin — 1 (Hirudo medicinalis) Modell von Hirudin (Stäbchen) im K …   Deutsch Wikipedia

  • Гепарин-индуцированная тромбоцитопения — Схематическое изображение …   Википедия

  • Desirudin — Hirudin 1 (Hirudo medicinalis), Lepirudin Modell von Hirudin (Stäbchen) im Komplex mit …   Deutsch Wikipedia

  • Anticoagulant — An anticoagulant is a substance that prevents coagulation (clotting) of blood. A group of pharmaceuticals called anticoagulants can be used in vivo as a medication for thrombotic disorders. Some anticoagulants are used in medical equipment, such… …   Wikipedia

  • Heparin-induced thrombocytopenia — Infobox Disease Name = PAGENAME Caption = DiseasesDB = ICD10 = ICD9 = (289.84) ICDO = OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = Heparin induced thrombocytopenia (HIT) with or without thrombosis (HITT) is thrombocytopenia (low …   Wikipedia

  • Hirudin — Structure of Hirudin in complex with Thrombin.[1] Hirudin …   Wikipedia

  • Direct thrombin inhibitor — Direct thrombin inhibitors (DTIs) are a class of medication that act as anticoagulants (delaying blood clotting) by directly inhibiting the enzyme thrombin. Some are in clinical use, while others are undergoing clinical development. Several… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”