- Boutonneuse fever
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Boutonneuse fever Classification and external resources
Typical eschar and spots on the leg of a patient with Boutonneuse fever[1]ICD-10 A77.1 ICD-9 082.1 DiseasesDB 31780 MeSH D001907 Boutonneuse fever (also called Mediterranean spotted fever, fièvre boutonneuse, or Marseilles fever or ' tick bite fever') is a fever as a result of a Rickettsia infection caused by the bacterium Rickettsia conorii and transmitted by the dog tick Rhipicephalus sanguineus. Boutonneuse fever can be seen in many places around the world, although it is endemic in countries surrounding the Mediterranean Sea. This disease was first described in Tunisia in 1910 by Conor and Bruch and was named boutonneuse (French for "spotty") due to its papular skin rash characteristics.[2][1]
Contents
Presentation
After an incubation period of around seven days, the disease manifests abruptly with chills, high fevers, muscular and articular pains, severe headache and photophobia. The location of the bite forms a black ulcerous crust (tache noire). Around the fourth day of the illness an exanthem (widespread rash) appears, first macular and then maculopapular and sometimes petechial.
Diagnosis
The diagnosis is made with serologic methods, either the classic Weil-Felix test (agglutination of Proteus OX strains ), ELISA or immunofluorescence assays in the bioptic material of the primary lesion.
Treatment
The illness can be treated with tetracyclines (doxycycline is the preferred treatment), chloramphenicol, macrolides or fluoroquinolones.
References
- ^ a b Rovery C; Brouqui P; Raoult D (2008). "Questions on Mediterranean Spotted Fever a Century after Its Discovery". Emerg Infect Dis 14: 1360–1367. doi:10.3201/eid1409.071133.
- ^ Conor, A & A Bruch (1910). "Une fièvre éruptive observée en Tunisie". Bull Soc Pathol Exot Filial 8: 492–496.
See also
External links
Zoonosis: Tick-borne diseases and mite-borne diseases Bacterial infection
(all G-)Rocky Mountain spotted fever · Ehrlichiosis (Human granulocytic, Human monocytic) · Boutonneuse feverViral infection Protozoan infection Neurotoxin General Tick infestationVectors TicksIxodes: Ixodes scapularis · Ixodes holocyclus · Ixodes pacificus · Ixodes ricinus
Dermacentor: Dermacentor variabilis · Dermacentor andersoni
Amblyomma: Amblyomma americanum · Amblyomma cajennense
other: Rhipicephalus sanguineusMitesLeptotrombidium deliense · Liponyssoides sanguineusM: IFT
helm,arth (acar)
helm, arth (lice), zoon
helm, arth
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