- Brazilian purpuric fever
Infobox_Disease
Name = Brazilian purpuric fever
Caption =
DiseasesDB =
ICD10 = ICD10|A|48|4|a|30
ICD9 =
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj =
eMedicineTopic =
MeshName =
MeshNumber =Brazilian purpuric fever (BPF) is an illness of children caused by the bacterium "Haemophilus influenzae" biogroup "aegyptius" [PMID 15784532] which causes
fulminant sepsis . It is mainly known fromBrazil but there have been recorded cases inAustralia .Causes
The causative bacterium is a
Gram-negative coccobacillus that usually causesconjunctivitis in the tropics. By as yet uncertain means the conjunctivitis can be the focus ofbacteremia and thus invasive disease. Brazilian purpuric fever is similar tomeningococcemia in presentation. Prostrating high fevers and chills, vomiting and gastrointestinal complaints progress rapidly to extensive purpura, septic shock and acidosis. Meningitis does not occur.Diagnosis and treatment
Diagnosis is made upon isolation of the bacterium from blood. Treatment is with
ampicillin pluschloramphenicol until sensitivities are known. The mortality rate is around 70% even with therapy.References
Wikimedia Foundation. 2010.