Suprofen

Suprofen: Suprofen

Systematic (IUPAC) name

(RS)-2-[4-(2-thienylcarbonyl)phenyl]propanoic acid

Clinical data

AHFS/Drugs.com Micromedex Detailed Consumer Information

Pregnancy cat. ?

Legal status ?

Pharmacokinetic data

Protein binding 20%

Identifiers

CAS number 40828-46-4^Y

ATC code M01AE07

PubChem CID 5359

DrugBank APRD00230

ChemSpider 5166^Y

UNII 988GU2F9PE^Y

KEGG D00452^Y

ChEBI CHEBI:9362^N

ChEMBL CHEMBL956^Y

Chemical data

Formula C₁₄H₁₂O₃S

Mol. mass 260.309 g/mol

SMILES eMolecules & PubChem

InChI

InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17)^Y
Key:MDKGKXOCJGEUJW-UHFFFAOYSA-N^Y

N(what is this?) (verify)

Suprofen is an NSAID marketed in a 1% solution under the trade name Profenal.

Uses

Suprofen was originally used as a tablet but has since been discontinued in that form.^[1] It is now used exclusively as a topical ophthalmic solution, typically to prevent miosis during and after ophthalmic surgery.

References

^ http://www.fda.gov/ora/compliance_ref/cpg/cpgdrg/cpg460-200.html Guidance for FDA Staff and Industry Compliance Policy Guides Manual Sec. 460.200

v · d · eNon-steroidal anti-inflammatory drug (NSAID) products (primarily M01A and M02A, also N02BA)

Salicylates
Aspirin (acetylsalicylic acid) • Aloxiprin • Benorylate • Diflunisal • Ethenzamide • Magnesium salicylate • Methyl salicylate • Salsalate • Salicin • Salicylamide • Sodium salicylate

Arylalkanoic acids
Diclofenac • Aceclofenac • Acemetacin • Alclofenac • Bromfenac • Etodolac • Indometacin • Indometacin farnesil • Nabumetone • Oxametacin • Proglumetacin • Sulindac • Tolmetin

2-Arylpropionic acids
(profens)
Ibuprofen • Alminoprofen • Benoxaprofen • Carprofen • Dexibuprofen • Dexketoprofen • Fenbufen • Fenoprofen • Flunoxaprofen • Flurbiprofen • Ibuproxam • Indoprofen^† • Ketoprofen • Ketorolac • Loxoprofen • Miroprofen • Naproxen • Oxaprozin • Pirprofen • Suprofen • Tarenflurbil • Tiaprofenic acid

N-Arylanthranilic acids
(fenamic acids)
Mefenamic acid • Flufenamic acid • Meclofenamic acid • Tolfenamic acid

Pyrazolidine derivatives
Phenylbutazone • Ampyrone • Azapropazone • Clofezone • Kebuzone • Metamizole • Mofebutazone • Oxyphenbutazone • Phenazone • Sulfinpyrazone

Oxicams
Piroxicam • Droxicam • Lornoxicam • Meloxicam • Tenoxicam • Ampiroxicam

COX -2 inhibitors
Celecoxib • Deracoxib^‡ • Etoricoxib • Firocoxib^‡ • Lumiracoxib^† • Parecoxib • Rofecoxib^† • Valdecoxib^†

Sulfonanilides
Nimesulide

Topically used products
Bendazac • Diclofenac • Etofenamate • Felbinac • Flurbiprofen • Ibuprofen • Indometacin • Ketoprofen • Naproxen • Piroxicam • Suprofen

COX-inhibiting nitric oxide donators
Naproxcinod

Others
Fluproquazone

Items listed in bold indicate initially developed compounds of specific groups. ^†Withdrawn drugs. ^‡Veterinary use medications.

v · d · eAnti-inflammatory products (M01A)

Pyrazolidine/Butylpyrazolidines
Ampyrone • Clofezone • Kebuzone • Metamizole • Mofebutazone • Oxyphenbutazone • Phenazone • Phenylbutazone • Sulfinpyrazone • Feprazone •

Acetic acid derivatives
and related substances
Aceclofenac • Acemetacin • Alclofenac • Bromfenac • Bumadizone • Bufexamac • Diclofenac • Difenpiramide • Etodolac • Fentiazac • Indometacin • Ketorolac • Lonazolac • Oxametacin • Proglumetacin • Sulindac • Tolmetin • Zomepirac • Amfenac

Oxicams
Ampiroxicam • Droxicam • Lornoxicam • Meloxicam • Piroxicam • Tenoxicam

Propionic acid derivatives
Alminoprofen • Benoxaprofen • Dexibuprofen • Dexketoprofen • Fenbufen • Fenoprofen • Flunoxaprofen • Flurbiprofen • Ibuprofen • Ibuproxam • Indoprofen • Ketoprofen • Naproxen • Oxaprozin • Pirprofen • Suprofen • Tiaprofenic acid

Fenamates
Flufenamic acid • Meclofenamic acid • Mefenamic acid • Tolfenamic acid • Niflumic acid • Morniflumate • Azapropazone •

Coxibs
Celecoxib • Etoricoxib • Lumiracoxib • Parecoxib • Rofecoxib • Valdecoxib

Other
Nabumetone • Glucosamine • Benzydamine • Glycosaminoglycan • Magnesium salicylate • Proquazone • Superoxide dismutase/Orgotein • Nimesulide • Diacerein • Tenidap • Oxaceprol • Chondroitin sulfate

M: MUS, DF+DRCT

anat (h/n, u, t/d, a/p, l)/phys/devp/hist

noco(m, s, c)/cong(d)/tumr, sysi/epon, injr

proc, drug (M1A/3)

This drug article relating to the musculoskeletal system is a stub. You can help Wikipedia by expanding it.

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Suprofen

Uses

References

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Systematic (IUPAC) name
(RS)-2-[4-(2-thienylcarbonyl)phenyl]propanoic acid
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Pregnancy cat.	?
Legal status	?
Pharmacokinetic data
Protein binding	20%
Identifiers
CAS number	40828-46-4^Y
ATC code	M01AE07
PubChem	CID 5359
DrugBank	APRD00230
ChemSpider	5166^Y
UNII	988GU2F9PE^Y
KEGG	D00452^Y
ChEBI	CHEBI:9362^N
ChEMBL	CHEMBL956^Y
Chemical data
Formula	C₁₄H₁₂O₃S
Mol. mass	260.309 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17)^Y Key:MDKGKXOCJGEUJW-UHFFFAOYSA-N^Y
N(what is this?) (verify)

Academic Dictionaries and Encyclopedias

Wikipedia

Suprofen

Uses

References

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