- mir-194 microRNA precursor family
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mir-194 microRNA precursor family Predicted secondary structure and sequence conservation of mir-194 Identifiers Symbol mir-194 Rfam RF00257 miRBase MI0000488 miRBase family MIPF0000055 Other data RNA type Gene; miRNA Domain(s) Eukaryota GO 0035195 0035068 SO 0001244 In molecular biology, miR-194 microRNA precursor is a small non-coding RNA gene that regulated gene expression. Its expression has been verified in mouse (MI0000236, MI0000733)[1] and in human (MI0000488, MI0000732).[2] mir-194 appears to be a vertebrate-specific miRNA and has now been predicted or experimentally confirmed in a range of vertebrate species (MIPF0000055). The mature microRNA is processed from the longer hairpin precursor by the Dicer enzyme. In this case, the mature sequence is excised from the 5' arm of the hairpin.
References
- ^ Lagos-Quintana, M; Rauhut R, Meyer J, Borkhardt A, Tuschl T (2003). "New microRNAs from mouse and human". RNA 9 (2): 175–179. doi:10.1261/rna.2146903. PMC 1370382. PMID 12554859. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1370382.
- ^ Michael, MZ; O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ (2003). "Reduced accumulation of specific microRNAs in colorectal neoplasia". Mol Cancer Res 1 (12): 882–891. PMID 14573789.
External links
miRNA precursor families 1-100 101-200 201+ Other Categories:- Molecular and cellular biology stubs
- MicroRNA
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