Mir-BHRF1-1 microRNA precursor family
- Mir-BHRF1-1 microRNA precursor family
The mir-BHRF1-1 microRNA precursor found in Human herpesvirus 4 (Epstein-Barr virus) and Cercopithicine herpesvirus 15. In Epstein-Barr virus, mir-BHRF1-1 is found in the 5' UTR of the BHRF1 (Bam HI fragment H rightward open reading frame 1) gene, which is known to encode a distant Bcl-2 homolog. The mature sequence is excised from the 5' arm of the hairpin. [cite journal | last = Pfeffer | first = S | coauthors = Zavolan M, Grasser FA, Chien M, Russo JJ, Ju J, John B, Enright AJ, Marks D, Sander C, Tuschl T | year = 2004 | title = Identification of Virus-Encoded MicroRNAs | journal = Science | volume = 304 | pages = 734–736 | pmid = 15118162 | doi = 10.1126/science.1096781]
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