Mir-166 microRNA precursor
- Mir-166 microRNA precursor
The plant mir-166 microRNA precursor is a small non-coding RNA gene. This microRNA (miRNA) has now been predicted or experimentally confirmed in a wide range of plant species ( [http://microrna.sanger.ac.uk/cgi-bin/sequences/mirna_summary.pl?fam=MIPF0000004 MIPF0000004] ). microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In this case the mature sequence comes from the 3' arm of the precursor, and both "Arabidopsis thaliana" and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences. The mature products are thought to have regulatory roles through complementarity to messenger RNA.
References
* [1] cite journal | last = Reinhart | first = BJ | coauthors = Weinstein EG, Rhoades MW, Bartel B, Bartel DP | year = 2002 | title = MicroRNAs in plants | journal = Genes Dev | volume = 16 | pages = 1616–1626 | pmid = 12101121 | doi = 10.1101/gad.1004402
* [2] cite journal | last = Ambros | first = V | year = 2001 | title = microRNAs: tiny regulators with great potential | journal = Cell | volume = 107 | pages = 823–826 | pmid = 11779458 | doi = 10.1016/S0092-8674(01)00616-X
External links
*
* [http://microrna.sanger.ac.uk/cgi-bin/sequences/mirna_summary.pl?fam=MIPF0000004 MIPF0000004]
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