Mir-30 microRNA precursor
- Mir-30 microRNA precursor
miR-30 microRNA precursor is a small non-coding RNA that regulates gene expression. Animal microRNAs are transcribed as ~70 nucleotide stem-loop precursor and subsequently processed by the Dicer enzyme to give a mature ~22 nucleotide product. In this case the mature sequence comes from both the 3' (miR-30) [cite journal | last = Lagos-Quintana | first = M | coauthors = Rauhut R, Lendeckel W, Tuschl T | year = 2001 | title = Identification of novel genes coding for small expressed RNAs | journal = Science | volume = 294 | pages = 853–858 | pmid = 11679670 | doi = 10.1126/science.1064921] and 5' (mir-97-6) [cite journal | last = Mourelatos | first = Z | coauthors = Dostie J, Paushkin S, Sharma A, Charroux B, Abel L, Rappsilber J, Mann M, Dreyfuss G | year = 2002 | title = miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs | journal = Genes Dev | volume = 16 | pages = 720–728 | pmid = 11914277 | doi = 10.1101/gad.974702] arms of the precursor. The products are thought to have regulatory roles through complementarity to mRNA [cite journal |author=Ambros V |title=microRNAs: tiny regulators with great potential |journal=Cell |volume=107 |issue=7 |pages=823–6 |year=2001 |pmid=11779458 |doi=] .]References
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