Mir-24 microRNA precursor family

Mir-24 microRNA precursor family

The miR-24 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a mature ~22 nucleotide product. In this case the mature sequence comes from the 3' arm of the precursor. The mature products are thought to have regulatory roles through complementarity to mRNA. miR-24 has been identified in human and mouse. [cite journal | last = Lagos-Quintana | first = M | coauthors = Rauhut R, Lendeckel W, Tuschl T | year = 2001 | title = Identification of novel genes coding for small expressed RNAs | journal = Science | volume = 294 | pages = 853–858 | pmid = 11679670 | doi = 10.1126/science.1064921]

References

* [2] cite journal | last = Ambros | first = V | year = 2001 | title = microRNAs: tiny regulators with great potential | journal = Cell | volume = 107 | pages = 823–826 | pmid = 11779458 | doi = 10.1016/S0092-8674(01)00616-X

External links

*
* [http://microrna.sanger.ac.uk/cgi-bin/sequences/mirna_summary.pl?fam=MIPF0000041 miRBase family MIPF0000041]


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”