- STYK1
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Serine/threonine/tyrosine kinase 1 Identifiers Symbols STYK1; DKFZp761P1010; NOK; SuRTK106 External IDs OMIM: 611433 MGI: 2141396 HomoloGene: 49545 GeneCards: STYK1 Gene EC number 2.7.10.2 Gene Ontology Molecular function • nucleotide binding
• non-membrane spanning protein tyrosine kinase activity
• ATP bindingCellular component • plasma membrane
• integral to membraneBiological process • protein amino acid phosphorylation Sources: Amigo / QuickGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 55359 243659 Ensembl ENSG00000060140 ENSMUSG00000032899 UniProt Q6J9G0 Q6J9G1 RefSeq (mRNA) NM_018423 NM_172891.2 RefSeq (protein) NP_060893 NP_766479.1 Location (UCSC) Chr 12:
10.77 – 10.83 MbChr 6:
131.25 – 131.3 MbPubMed search [1] [2] Tyrosine-protein kinase STYK1 is an enzyme that in humans is encoded by the STYK1 gene.[1][2]
References
- ^ Ye X, Ji C, Huang Q, Cheng C, Tang R, Xu J, Zeng L, Dai J, Wu Q, Gu S, Xie Y, Mao Y (Jul 2003). "Isolation and characterization of a human putative receptor protein kinase cDNA STYK1". Mol Biol Rep 30 (2): 91–6. doi:10.1023/A:1023934017174. PMID 12841579.
- ^ "Entrez Gene: STYK1 serine/threonine/tyrosine kinase 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55359.
Further reading
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310948.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=311072.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1083732.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Liu L, Yu XZ, Li TS, et al. (2004). "A novel protein tyrosine kinase NOK that shares homology with platelet- derived growth factor/fibroblast growth factor receptors induces tumorigenesis and metastasis in nude mice.". Cancer Res. 64 (10): 3491–9. doi:10.1158/0008-5472.CAN-03-2106. PMID 15150103.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528930.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1347501.
- Amachika T, Kobayashi D, Moriai R, et al. (2007). "Diagnostic relevance of overexpressed mRNA of novel oncogene with kinase-domain (NOK) in lung cancers.". Lung Cancer 56 (3): 337–40. doi:10.1016/j.lungcan.2007.01.002. PMID 17298854.
Protein kinases: tyrosine kinases (EC 2.7.10) Receptor tyrosine kinases (EC 2.7.10.1) Insulin receptor familyPDGF receptor familyFGF receptor familyVEGF receptors familyHGF receptor familyTrk receptor familyEPH receptor familyLTK receptor familyLTK · ALKTIE receptor familyROR receptor familyROR1 · ROR2DDR receptor familyPTK7 receptor familyRYK receptor familyMuSK receptor familyROS receptor familyAATYK receptor familyAXL receptor familyRET receptor familyuncatagorisedSTYK1Non-receptor tyrosine kinases (EC 2.7.10.2) ABL familyACK familyACK1 · TNK1CSK familyFAK familyFES familyFRK familyJAK familySRC-A familySRC-B familyTEC familySYK familyCategories:- Human proteins
- Chromosome 12 gene stubs
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