EPH receptor B1

EPH receptor B1, also known as EPHB1, is a human gene.cite web | title = Entrez Gene: EPHB1 EPH receptor B1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2047| accessdate = ]

PBB_Summary
section_title =
summary_text = Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.cite web | title = Entrez Gene: EPHB1 EPH receptor B1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2047| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Flanagan JG, Vanderhaeghen P |title=The ephrins and Eph receptors in neural development. |journal=Annu. Rev. Neurosci. |volume=21 |issue= |pages= 309–45 |year= 1998 |pmid= 9530499 |doi= 10.1146/annurev.neuro.21.1.309
*cite journal | author=Zhou R |title=The Eph family receptors and ligands. |journal=Pharmacol. Ther. |volume=77 |issue= 3 |pages= 151–81 |year= 1998 |pmid= 9576626 |doi=
*cite journal | author=Abrahamson DR, Robert B, Hyink DP, "et al." |title=Origins and formation of microvasculature in the developing kidney. |journal=Kidney Int. Suppl. |volume=67 |issue= |pages= S7–11 |year= 1998 |pmid= 9736245 |doi=
*cite journal | author=Holder N, Klein R |title=Eph receptors and ephrins: effectors of morphogenesis. |journal=Development |volume=126 |issue= 10 |pages= 2033–44 |year= 1999 |pmid= 10207129 |doi=
*cite journal | author=Wilkinson DG |title=Eph receptors and ephrins: regulators of guidance and assembly. |journal=Int. Rev. Cytol. |volume=196 |issue= |pages= 177–244 |year= 2000 |pmid= 10730216 |doi=
*cite journal | author=Xu Q, Mellitzer G, Wilkinson DG |title=Roles of Eph receptors and ephrins in segmental patterning. |journal=Philos. Trans. R. Soc. Lond., B, Biol. Sci. |volume=355 |issue= 1399 |pages= 993–1002 |year= 2001 |pmid= 11128993 |doi= 10.1098/rstb.2000.0635
*cite journal | author=Wilkinson DG |title=Multiple roles of EPH receptors and ephrins in neural development. |journal=Nat. Rev. Neurosci. |volume=2 |issue= 3 |pages= 155–64 |year= 2001 |pmid= 11256076 |doi=
*cite journal | author=Larose L, Gish G, Shoelson S, Pawson T |title=Identification of residues in the beta platelet-derived growth factor receptor that confer specificity for binding to phospholipase C-gamma 1. |journal=Oncogene |volume=8 |issue= 9 |pages= 2493–9 |year= 1993 |pmid= 7689724 |doi=
*cite journal | author=Davis S, Gale NW, Aldrich TH, "et al." |title=Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. |journal=Science |volume=266 |issue= 5186 |pages= 816–9 |year= 1994 |pmid= 7973638 |doi=
*cite journal | author=Beckmann MP, Cerretti DP, Baum P, "et al." |title=Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors. |journal=EMBO J. |volume=13 |issue= 16 |pages= 3757–62 |year= 1994 |pmid= 8070404 |doi=
*cite journal | author=Cerretti DP, Vanden Bos T, Nelson N, "et al." |title=Isolation of LERK-5: a ligand of the eph-related receptor tyrosine kinases. |journal=Mol. Immunol. |volume=32 |issue= 16 |pages= 1197–205 |year= 1996 |pmid= 8559144 |doi=
*cite journal | author=Tang XX, Biegel JA, Nycum LM, "et al." |title=cDNA cloning, molecular characterization, and chromosomal localization of NET(EPHT2), a human EPH-related receptor protein-tyrosine kinase gene preferentially expressed in brain. |journal=Genomics |volume=29 |issue= 2 |pages= 426–37 |year= 1996 |pmid= 8666391 |doi= 10.1006/geno.1995.9985
*cite journal | author=Gale NW, Holland SJ, Valenzuela DM, "et al." |title=Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. |journal=Neuron |volume=17 |issue= 1 |pages= 9–19 |year= 1996 |pmid= 8755474 |doi=
*cite journal | author=Stein E, Cerretti DP, Daniel TO |title=Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells. |journal=J. Biol. Chem. |volume=271 |issue= 38 |pages= 23588–93 |year= 1996 |pmid= 8798570 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Kozlosky CJ, VandenBos T, Park L, "et al." |title=LERK-7: a ligand of the Eph-related kinases is developmentally regulated in the brain. |journal=Cytokine |volume=9 |issue= 8 |pages= 540–9 |year= 1997 |pmid= 9245480 |doi= 10.1006/cyto.1997.0199
*cite journal | author= |title=Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee. |journal=Cell |volume=90 |issue= 3 |pages= 403–4 |year= 1997 |pmid= 9267020 |doi=
*cite journal | author=Stein E, Huynh-Do U, Lane AA, "et al." |title=Nck recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase. |journal=J. Biol. Chem. |volume=273 |issue= 3 |pages= 1303–8 |year= 1998 |pmid= 9430661 |doi=
*cite journal | author=Stein E, Lane AA, Cerretti DP, "et al." |title=Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses. |journal=Genes Dev. |volume=12 |issue= 5 |pages= 667–78 |year= 1998 |pmid= 9499402 |doi=

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