ABL2

V-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene), also known as ABL2, is a human gene.cite web | title = Entrez Gene: ABL2 v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27| accessdate = ]

PBB_Summary
section_title =
summary_text = ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length.cite web | title = Entrez Gene: ABL2 v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Pendergast AM |title=The Abl family kinases: mechanisms of regulation and signaling. |journal=Adv. Cancer Res. |volume=85 |issue= |pages= 51–100 |year= 2003 |pmid= 12374288 |doi=
*cite journal | author=Muller AJ, Pendergast AM, Havlik MH, "et al." |title=A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction. |journal=Mol. Cell. Biol. |volume=12 |issue= 11 |pages= 5087–93 |year= 1992 |pmid= 1383690 |doi=
*cite journal | author=Kruh GD, Perego R, Miki T, Aaronson SA |title=The complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinases. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 15 |pages= 5802–6 |year= 1990 |pmid= 2198571 |doi=
*cite journal | author=Kruh GD, King CR, Kraus MH, "et al." |title=A novel human gene closely related to the abl proto-oncogene. |journal=Science |volume=234 |issue= 4783 |pages= 1545–8 |year= 1987 |pmid= 3787260 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Wang B, Kruh GD |title=Subcellular localization of the Arg protein tyrosine kinase. |journal=Oncogene |volume=13 |issue= 1 |pages= 193–7 |year= 1996 |pmid= 8700546 |doi=
*cite journal | author=Wang B, Mysliwiec T, Feller SM, "et al." |title=Proline-rich sequences mediate the interaction of the Arg protein tyrosine kinase with Crk. |journal=Oncogene |volume=13 |issue= 7 |pages= 1379–85 |year= 1996 |pmid= 8875975 |doi=
*cite journal | author=Wang B, Golemis EA, Kruh GD |title=ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks. |journal=J. Biol. Chem. |volume=272 |issue= 28 |pages= 17542–50 |year= 1997 |pmid= 9211900 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Koval AP, Blakesley VA, Roberts CT, "et al." |title=Interaction in vitro of the product of the c-Crk-II proto-oncogene with the insulin-like growth factor I receptor. |journal=Biochem. J. |volume=330 ( Pt 2) |issue= |pages= 923–32 |year= 1998 |pmid= 9480911 |doi=
*cite journal | author=Hashimoto Y, Katayama H, Kiyokawa E, "et al." |title=Phosphorylation of CrkII adaptor protein at tyrosine 221 by epidermal growth factor receptor. |journal=J. Biol. Chem. |volume=273 |issue= 27 |pages= 17186–91 |year= 1998 |pmid= 9642287 |doi=
*cite journal | author=Danial NN, Losman JA, Lu T, "et al." |title=Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation. |journal=Mol. Cell. Biol. |volume=18 |issue= 11 |pages= 6795–804 |year= 1998 |pmid= 9774693 |doi=
*cite journal | author=Cao C, Ren X, Kharbanda S, "et al." |title=The ARG tyrosine kinase interacts with Siva-1 in the apoptotic response to oxidative stress. |journal=J. Biol. Chem. |volume=276 |issue= 15 |pages= 11465–8 |year= 2001 |pmid= 11278261 |doi= 10.1074/jbc.C100050200
*cite journal | author=Yu HH, Zisch AH, Dodelet VC, Pasquale EB |title=Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor. |journal=Oncogene |volume=20 |issue= 30 |pages= 3995–4006 |year= 2001 |pmid= 11494128 |doi= 10.1038/sj.onc.1204524
*cite journal | author=Endo A, Nagashima K, Kurose H, "et al." |title=Sphingosine 1-phosphate induces membrane ruffling and increases motility of human umbilical vein endothelial cells via vascular endothelial growth factor receptor and CrkII. |journal=J. Biol. Chem. |volume=277 |issue= 26 |pages= 23747–54 |year= 2002 |pmid= 11956190 |doi= 10.1074/jbc.M111794200
*cite journal | author=Abassi YA, Vuori K |title=Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling. |journal=EMBO J. |volume=21 |issue= 17 |pages= 4571–82 |year= 2002 |pmid= 12198159 |doi=
*cite journal | author=Bianchi C, Muradore I, Corizzato M, "et al." |title=The expression of the non-receptor tyrosine kinases Arg and c-abl is differently modulated in B lymphoid cells at different stages of differentiation. |journal=FEBS Lett. |volume=527 |issue= 1-3 |pages= 216–222 |year= 2002 |pmid= 12220663 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Salomon AR, Ficarro SB, Brill LM, "et al." |title=Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 2 |pages= 443–8 |year= 2003 |pmid= 12522270 |doi= 10.1073/pnas.2436191100

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