FER (gene)

Fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94), also known as FER, is a human gene.cite web | title = Entrez Gene: FER fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2241| accessdate = ]

PBB_Summary
section_title =
summary_text = Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.cite web | title = Entrez Gene: FER fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2241| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Greer P |title=Closing in on the biological functions of Fps/Fes and Fer. |journal=Nat. Rev. Mol. Cell Biol. |volume=3 |issue= 4 |pages= 278–89 |year= 2002 |pmid= 11994747 |doi= 10.1038/nrm783
*cite journal | author=Nishisho I, Nakamura Y, Miyoshi Y, "et al." |title=Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. |journal=Science |volume=253 |issue= 5020 |pages= 665–9 |year= 1991 |pmid= 1651563 |doi=
*cite journal | author=Warrington JA, Hall LV, Hinton LM, "et al." |title=Radiation hybrid map of 13 loci on the long arm of chromosome 5. |journal=Genomics |volume=11 |issue= 3 |pages= 701–8 |year= 1992 |pmid= 1663488 |doi=
*cite journal | author=Hao QL, Ferris DK, White G, "et al." |title=Nuclear and cytoplasmic location of the FER tyrosine kinase. |journal=Mol. Cell. Biol. |volume=11 |issue= 2 |pages= 1180–3 |year= 1991 |pmid= 1990274 |doi=
*cite journal | author=Krolewski JJ, Lee R, Eddy R, "et al." |title=Identification and chromosomal mapping of new human tyrosine kinase genes. |journal=Oncogene |volume=5 |issue= 3 |pages= 277–82 |year= 1990 |pmid= 2156206 |doi=
*cite journal | author=Morris C, Heisterkamp N, Hao QL, "et al." |title=The human tyrosine kinase gene (FER) maps to chromosome 5 and is deleted in myeloid leukemias with a del(5q). |journal=Cytogenet. Cell Genet. |volume=53 |issue= 4 |pages= 196–200 |year= 1990 |pmid= 2209086 |doi=
*cite journal | author=Pawson T, Letwin K, Lee T, "et al." |title=The FER gene is evolutionarily conserved and encodes a widely expressed member of the FPS/FES protein-tyrosine kinase family. |journal=Mol. Cell. Biol. |volume=9 |issue= 12 |pages= 5722–5 |year= 1990 |pmid= 2685575 |doi=
*cite journal | author=Hao QL, Heisterkamp N, Groffen J |title=Isolation and sequence analysis of a novel human tyrosine kinase gene. |journal=Mol. Cell. Biol. |volume=9 |issue= 4 |pages= 1587–93 |year= 1989 |pmid= 2725517 |doi=
*cite journal | author=Brunati AM, Pinna LA |title=Characterization of four tyrosine protein kinases from the particulate fraction of rat spleen. |journal=Eur. J. Biochem. |volume=172 |issue= 2 |pages= 451–7 |year= 1988 |pmid= 3350007 |doi=
*cite journal | author=Meggio F, Brunati AM, Pinna LA |title=Polycation-dependent, Ca2+-antagonized phosphorylation of calmodulin by casein kinase-2 and a spleen tyrosine protein kinase. |journal=FEBS Lett. |volume=215 |issue= 2 |pages= 241–6 |year= 1987 |pmid= 3472906 |doi=
*cite journal | author=Kim L, Wong TW |title=The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors. |journal=Mol. Cell. Biol. |volume=15 |issue= 8 |pages= 4553–61 |year= 1995 |pmid= 7623846 |doi=
*cite journal | author=Lee ST, Strunk KM, Spritz RA |title=A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes. |journal=Oncogene |volume=8 |issue= 12 |pages= 3403–10 |year= 1993 |pmid= 8247543 |doi=
*cite journal | author=Kim L, Wong TW |title=Growth factor-dependent phosphorylation of the actin-binding protein cortactin is mediated by the cytoplasmic tyrosine kinase FER. |journal=J. Biol. Chem. |volume=273 |issue= 36 |pages= 23542–8 |year= 1998 |pmid= 9722593 |doi=
*cite journal | author=Rosato R, Veltmaat JM, Groffen J, Heisterkamp N |title=Involvement of the tyrosine kinase fer in cell adhesion. |journal=Mol. Cell. Biol. |volume=18 |issue= 10 |pages= 5762–70 |year= 1998 |pmid= 9742093 |doi=
*cite journal | author=Schwartz Y, Ben-Dor I, Navon A, "et al." |title=Tyrosine phosphorylation of the TATA element modulatory factor by the FER nuclear tyrosine kinases. |journal=FEBS Lett. |volume=434 |issue= 3 |pages= 339–45 |year= 1998 |pmid= 9742951 |doi=
*cite journal | author=Huang C, Liu J, Haudenschild CC, Zhan X |title=The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells. |journal=J. Biol. Chem. |volume=273 |issue= 40 |pages= 25770–6 |year= 1998 |pmid= 9748248 |doi=
*cite journal | author=Corti C, Leclerc L'Hostis E, Quadroni M, "et al." |title=Tyrosine phosphorylation modulates the interaction of calmodulin with its target proteins. |journal=Eur. J. Biochem. |volume=262 |issue= 3 |pages= 790–802 |year= 1999 |pmid= 10411641 |doi=
*cite journal | author=Priel-Halachmi S, Ben-Dor I, Shpungin S, "et al." |title=FER kinase activation of Stat3 is determined by the N-terminal sequence. |journal=J. Biol. Chem. |volume=275 |issue= 37 |pages= 28902–10 |year= 2000 |pmid= 10878010 |doi= 10.1074/jbc.M003402200
*cite journal | author=Kapus A, Di Ciano C, Sun J, "et al." |title=Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites. The role of Fyn and FER kinases. |journal=J. Biol. Chem. |volume=275 |issue= 41 |pages= 32289–98 |year= 2000 |pmid= 10921917 |doi= 10.1074/jbc.M003172200
*cite journal | author=Orlovsky K, Ben-Dor I, Priel-Halachmi S, "et al." |title=N-terminal sequences direct the autophosphorylation states of the FER tyrosine kinases in vivo. |journal=Biochemistry |volume=39 |issue= 36 |pages= 11084–91 |year= 2000 |pmid= 10998246 |doi=

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