ROS1 (gene)

V-ros UR2 sarcoma virus oncogene homolog 1 (avian), also known as ROS1, is a human gene.cite web | title = Entrez Gene: ROS1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6098| accessdate = ]

PBB_Summary
section_title =
summary_text = This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.cite web | title = Entrez Gene: ROS1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6098| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Galland F, Stefanova M, Lafage M, Birnbaum D |title=Localization of the 5' end of the MCF2 oncogene to human chromosome 15q15----q23. |journal=Cytogenet. Cell Genet. |volume=60 |issue= 2 |pages= 114–6 |year= 1992 |pmid= 1611909 |doi=
*cite journal | author=Birchmeier C, O'Neill K, Riggs M, Wigler M |title=Characterization of ROS1 cDNA from a human glioblastoma cell line. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 12 |pages= 4799–803 |year= 1990 |pmid= 2352949 |doi=
*cite journal | author=Sharma S, Birchmeier C, Nikawa J, "et al." |title=Characterization of the ros1-gene products expressed in human glioblastoma cell lines. |journal=Oncogene Res. |volume=5 |issue= 2 |pages= 91–100 |year= 1990 |pmid= 2691958 |doi=
*cite journal | author=Birchmeier C, Sharma S, Wigler M |title=Expression and rearrangement of the ROS1 gene in human glioblastoma cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 24 |pages= 9270–4 |year= 1988 |pmid= 2827175 |doi=
*cite journal | author=Matsushime H, Wang LH, Shibuya M |title=Human c-ros-1 gene homologous to the v-ros sequence of UR2 sarcoma virus encodes for a transmembrane receptorlike molecule. |journal=Mol. Cell. Biol. |volume=6 |issue= 8 |pages= 3000–4 |year= 1987 |pmid= 3023956 |doi=
*cite journal | author=Satoh H, Yoshida MC, Matsushime H, "et al." |title=Regional localization of the human c-ros-1 on 6q22 and flt on 13q12. |journal=Jpn. J. Cancer Res. |volume=78 |issue= 8 |pages= 772–5 |year= 1987 |pmid= 3115921 |doi=
*cite journal | author=Birchmeier C, Birnbaum D, Waitches G, "et al." |title=Characterization of an activated human ros gene. |journal=Mol. Cell. Biol. |volume=6 |issue= 9 |pages= 3109–16 |year= 1986 |pmid= 3785223 |doi=
*cite journal | author=Sonnenberg-Riethmacher E, Walter B, Riethmacher D, "et al." |title=The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis. |journal=Genes Dev. |volume=10 |issue= 10 |pages= 1184–93 |year= 1996 |pmid= 8675006 |doi=
*cite journal | author=Zeng L, Sachdev P, Yan L, "et al." |title=Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation. |journal=Mol. Cell. Biol. |volume=20 |issue= 24 |pages= 9212–24 |year= 2001 |pmid= 11094073 |doi=
*cite journal | author=Keilhack H, Müller M, Böhmer SA, "et al." |title=Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1. |journal=J. Cell Biol. |volume=152 |issue= 2 |pages= 325–34 |year= 2001 |pmid= 11266449 |doi=
*cite journal | author=Charest A, Kheifets V, Park J, "et al." |title=Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 3 |pages= 916–21 |year= 2003 |pmid= 12538861 |doi= 10.1073/pnas.242741799
*cite journal | author=Charest A, Lane K, McMahon K, "et al." |title=Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21). |journal=Genes Chromosomes Cancer |volume=37 |issue= 1 |pages= 58–71 |year= 2003 |pmid= 12661006 |doi= 10.1002/gcc.10207
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Légaré C, Sullivan R |title=Expression and localization of c-ros oncogene along the human excurrent duct. |journal=Mol. Hum. Reprod. |volume=10 |issue= 9 |pages= 697–703 |year= 2005 |pmid= 15235104 |doi= 10.1093/molehr/gah087
*cite journal | author=Biskup C, Böhmer A, Pusch R, "et al." |title=Visualization of SHP-1-target interaction. |journal=J. Cell. Sci. |volume=117 |issue= Pt 21 |pages= 5165–78 |year= 2005 |pmid= 15456853 |doi= 10.1242/jcs.01397
*cite journal | author=Girish V, Sachdeva N, Minz RW, "et al." |title=Bcl2 and ROS1 expression in human meningiomas: an analysis with respect to histological subtype. |journal=Indian journal of pathology & microbiology |volume=48 |issue= 3 |pages= 325–30 |year= 2006 |pmid= 16761743 |doi=

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