C-src tyrosine kinase

C-src tyrosine kinase

C-src tyrosine kinase, also known as CSK, is a human protein and gene. It includes an SH2 domain, an SH3 domain, and a tyrosine kinase domain. This protein specifically phosphorylates Tyr-504 residue on human leukocyte-specific protein tyrosine kinase, which acts as a negative regulatory site. It may also act on the LYN and FYN kinases.

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ee also

* Src (gene)
* Tyrosine kinase

Further reading

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*cite journal | author=Mustelin T, Taskén K |title=Positive and negative regulation of T-cell activation through kinases and phosphatases. |journal=Biochem. J. |volume=371 |issue= Pt 1 |pages= 15–27 |year= 2003 |pmid= 12485116 |doi= 10.1042/BJ20021637

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