- PTK7
PTK7 protein tyrosine kinase 7, also known as PTK7, is a human
gene .cite web | title = Entrez Gene: PTK7 PTK7 protein tyrosine kinase 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5754| accessdate = ]PBB_Summary
section_title =
summary_text = Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.cite web | title = Entrez Gene: PTK7 PTK7 protein tyrosine kinase 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5754| accessdate = ]References
Further reading
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citations =
*cite journal | author=Mossie K, Jallal B, Alves F, "et al." |title=Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family. |journal=Oncogene |volume=11 |issue= 10 |pages= 2179–84 |year= 1995 |pmid= 7478540 |doi=
*cite journal | author=Lee ST, Strunk KM, Spritz RA |title=A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes. |journal=Oncogene |volume=8 |issue= 12 |pages= 3403–10 |year= 1993 |pmid= 8247543 |doi=
*cite journal | author=Park SK, Lee HS, Lee ST |title=Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG. |journal=J. Biochem. |volume=119 |issue= 2 |pages= 235–9 |year= 1997 |pmid= 8882711 |doi=
*cite journal | author=Banga SS, Ozer HL, Park SK, Lee ST |title=Assignment of PTK7 encoding a receptor protein tyrosine kinase-like molecule to human chromosome 6p21.1-->p12.2 by fluorescence in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=76 |issue= 1-2 |pages= 43–4 |year= 1997 |pmid= 9154124 |doi=
*cite journal | author=Jung JW, Ji AR, Lee J, "et al." |title=Organization of the human PTK7 gene encoding a receptor protein tyrosine kinase-like molecule and alternative splicing of its mRNA. |journal=Biochim. Biophys. Acta |volume=1579 |issue= 2-3 |pages= 153–63 |year= 2003 |pmid= 12427550 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zhang H, Li XJ, Martin DB, Aebersold R |title=Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. |journal=Nat. Biotechnol. |volume=21 |issue= 6 |pages= 660–6 |year= 2003 |pmid= 12754519 |doi= 10.1038/nbt827
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Kobus FJ, Fleming KG |title=The GxxxG-containing transmembrane domain of the CCK4 oncogene does not encode preferential self-interactions. |journal=Biochemistry |volume=44 |issue= 5 |pages= 1464–70 |year= 2005 |pmid= 15683231 |doi= 10.1021/bi048076l
*cite journal | author=Katoh M, Katoh M |title=Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: transcriptional mechanism of PTK7 in colorectal cancer and that of SEMA6A in undifferentiated ES cells. |journal=Int. J. Mol. Med. |volume=20 |issue= 3 |pages= 405–9 |year= 2007 |pmid= 17671748 |doi=PBB_Controls
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