3-Phosphoglyceric acid

3-Phosphoglyceric acid
3-Phosphoglyceric acid
IUPAC name
(2R)-2-Hydroxy-3-phosphonooxypropanoic acid
Identifiers
CAS number 820-11-1 N
PubChem 439183
ChemSpider 388326 YesY
ChEBI CHEBI:17794 YesY
ChEMBL CHEMBL1160563 YesY
Jmol-3D images Image 1
Properties
Molecular formula C3H7O7P
Molar mass 186.06 g mol−1
 N acid (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

3-Phosphoglyceric acid (3PG), or glycerate 3-phosphate (GP), is a biochemically significant 3-carbon molecule that is a metabolic intermediate in both glycolysis and the Calvin cycle.[citation needed] This chemical is often termed PGA when referring to the Calvin cycle. 3-Phosphoglycerate is the resultant of the split of 6-carbon intermediate that is so unstable that it splits instantly. And two 3-phosphoglycerate molecules are produced for each molecule of CO2.

Contents

Glycolysis

1,3-bisphospho-D-glycerate 3-phosphoglycerate kinase 3-phospho-D-glycerate Phosphoglyceromutase 2-phospho-D-glycerate
1,3-bisphospho-D-glycerate wpmp.png   3-phospho-D-glycerate wpmp.png   2-phospho-D-glycerate wpmp.png
ADP ATP
Biochem reaction arrow reversible YYYY horiz med.png Biochem reaction arrow reversible NNNN horiz med.png
ADP ATP
   
  3-phosphoglycerate kinase   Phosphoglyceromutase

Compound C00236 at KEGG Pathway Database. Enzyme 2.7.2.3 at KEGG Pathway Database. Compound C00197 at KEGG Pathway Database. Enzyme 5.4.2.1 at KEGG Pathway Database. Compound C00631 at KEGG Pathway Database.

Calvin cycle

In the Calvin cycle, two glycerate 3-phosphate molecules are reduced to form two molecules of glyceraldehyde 3-phosphate (PGAL). This is the first compound formed during the C3 or Calvin cycle. It is a reactive biomolecule that is easily reduced.

Amino acid synthesis

Glycerate 3-phosphate is also a precursor for serine, which, in turn, can create cysteine and glycine through the homocysteine cycle.

See also


v · d · eGlycolysis Metabolic Pathway
Glucose Hexokinase Glucose 6-phosphate Glucose-6-phosphate isomerase Fructose 6-phosphate phosphofructokinase-1 Fructose 1,6-bisphosphate Fructose bisphosphate aldolase
D-glucose wpmp.png ATP ADP Alpha-D-glucose-6-phosphate wpmp.png Beta-D-fructose-6-phosphate wpmp.png ATP ADP Beta-D-fructose-1,6-bisphosphate wpmp.png
Biochem reaction arrow foward YYNN horiz med.svg GG-Pfeil 1.svg Biochem reaction arrow foward YYNN horiz med.svg GG-Pfeil 1.svg
Dihydroxyacetone phosphate Glyceraldehyde 3-phosphate Triosephosphate isomerase Glyceraldehyde 3-phosphate Glyceraldehyde-3-phosphate dehydrogenase 1,3-Bisphosphoglycerate
Glycerone-phosphate wpmp.png D-glyceraldehyde-3-phosphate wpmp.png D-glyceraldehyde-3-phosphate wpmp.png NAD+ + Pi NADH + H+ 1,3-bisphospho-D-glycerate wpmp.png
+ GG-Pfeil 1.svg 2 Biochem reaction arrow reversible YYYY horiz med.svg 2
Phosphoglycerate kinase 3-Phosphoglycerate Phosphoglycerate mutase 2-Phosphoglycerate Phosphopyruvate hydratase(Enolase) Phosphoenolpyruvate Pyruvate kinase Pyruvate
ADP ATP 3-phospho-D-glycerate wpmp.png 2-phospho-D-glycerate wpmp.png H2O Phosphoenolpyruvate wpmp.png ADP ATP Pyruvic-acid-2D-skeletal.svg
Biochem reaction arrow reversible YYYY horiz med.svg 2 GG-Pfeil 1.svg 2 Biochem reaction arrow reversible NYYN horiz med.png 2 Biochem reaction arrow foward YYNN horiz med.svg 2

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
v · Amino acid metabolism metabolic intermediates
K→acetyl-CoA
G
G→pyruvate→citrate

3-Phosphoglyceric acid

glycine→creatine: Glycocyamine · Phosphocreatine · Creatinine
G→glutamate→
α-ketoglutarate
other
G→fumarate
G→oxaloacetate
Other

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
biochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/i


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