Kynurenine

Kynurenine

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ImageFile=Kynurenine.svg
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IUPACName=2-amino-4-(2-aminophenyl)- 4-oxo-butanoic acid
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Section1= Chembox Identifiers
CASNo=343-65-7
PubChem=846
SMILES=C1=CC=C(C(=C1)C(=O)CC(C(=O)O)N)N
MeSHName=Kynurenine
Section2= Chembox Properties
Formula=C10H12N2O3
MolarMass=208.214 g/mol
Appearance=
Density=
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Section3= Chembox Hazards
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Kynurenine is a metabolite of the amino acid tryptophan used in the production of niacin. It has been associated with tics.

Kynureninase catabolizes the conversion of kynurenine into anthranilic acid while kynurenine—oxoglutarate transaminase (also known as Kynurenine amino-transferase and glutamine transaminase K, GTK) catabolizes its conversion into kynurenic acid and kynurenine 3-hydroxylase - to 3-hydroxykynurenine.

ee also

*indoleamine 2,3-dioxygenase
*N'-formylkynurenine


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Look at other dictionaries:

  • Kynurénine — Énantiomère R (D) de la kynurénine (à gauche) et S kynurénine (L) (à droite) Général …   Wikipédia en Français

  • Kynurenine — Général Nom IUPAC 2 amino 4 (2 aminophenyl) 4 oxo butanoic acid …   Wikipédia en Français

  • kynurenine — kinureninas statusas T sritis chemija formulė H₂NC₆H₄COCH₂CH(NH₂)COOH atitikmenys: angl. kynurenine rus. кинуренин ryšiai: sinonimas – 2 amino 4 (4 aminofenil) 4 oksobutano rūgštis …   Chemijos terminų aiškinamasis žodynas

  • Kynurenine 3-monooxygenase — In enzymology, a kynurenine 3 monooxygenase (EC number|1.14.13.9) is an enzyme that catalyzes the chemical reaction:L kynurenine + NADPH + H+ + O2 ightleftharpoons 3 hydroxy L kynurenine + NADP+ + H2OThe 4 substrates of this enzyme are L… …   Wikipedia

  • Kynurenine-oxoglutarate transaminase — In enzymology, a kynurenine oxoglutarate transaminase (EC number|2.6.1.7) is an enzyme that catalyzes the chemical reaction:L kynurenine + 2 oxoglutarate ightleftharpoons 4 (2 aminophenyl) 2,4 dioxobutanoate + L glutamateThus, the two substrates… …   Wikipedia

  • Kynurenine-glyoxylate transaminase — In enzymology, a kynurenine glyoxylate transaminase (EC number|2.6.1.63) is an enzyme that catalyzes the chemical reaction:L kynurenine + glyoxylate ightleftharpoons 4 (2 aminophenyl) 2,4 dioxobutanoate + glycineThus, the two substrates of this… …   Wikipedia

  • Kynurenine 7,8-hydroxylase — In enzymology, a kynurenine 7,8 hydroxylase (EC number|1.14.99.2) is an enzyme that catalyzes the chemical reaction:kynurenate + AH2 + O2 ightleftharpoons 7,8 dihydro 7,8 dihydroxykynurenate + AThe 3 substrates of this enzyme are kynurenate, AH2 …   Wikipedia

  • kynurenine 3-hydroxylase — kyn·ure·nine 3 hy·drox·y·lase (kīn uґrə nēn″ hi drokґsĭ lās) kynurenine 3 monooxygenase …   Medical dictionary

  • kynurenine 3-monooxygenase — kyn·ure·nine 3 mono·oxy·gen·ase (kīn uґrə nēn″ mon″o okґsĭ jən ās) [EC 1.14.13.9] an enzyme of the oxidoreductase class that catalyzes the hydroxylation of kynurenine as a step in the metabolism of… …   Medical dictionary

  • kynurenine — noun A metabolite, 2 amino 4 (2 aminophenyl) 4 oxo butanoic acid, that is an intermediate in the conversion of tryptophan to niacin See Also: kynurenic acid …   Wiktionary

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