Kynurenine 7,8-hydroxylase

Kynurenine 7,8-hydroxylase

In enzymology, a kynurenine 7,8-hydroxylase (EC number|1.14.99.2) is an enzyme that catalyzes the chemical reaction

:kynurenate + AH2 + O2 ightleftharpoons 7,8-dihydro-7,8-dihydroxykynurenate + A

The 3 substrates of this enzyme are kynurenate, AH2, and O2, whereas its two products are 7,8-dihydro-7,8-dihydroxykynurenate and A.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating). Other names in common use include kynurenic acid hydroxylase, kynurenic hydroxylase, and kynurenate 7,8-hydroxylase. This enzyme participates in tryptophan metabolism.

References

*

External links

::"The CAS registry number for this enzyme class is CAS registry|9029-63-4."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Kynurénine — Énantiomère R (D) de la kynurénine (à gauche) et S kynurénine (L) (à droite) Général …   Wikipédia en Français

  • Kynurenine — Général Nom IUPAC 2 amino 4 (2 aminophenyl) 4 oxo butanoic acid …   Wikipédia en Français

  • Kynurenine 3-monooxygenase — In enzymology, a kynurenine 3 monooxygenase (EC number|1.14.13.9) is an enzyme that catalyzes the chemical reaction:L kynurenine + NADPH + H+ + O2 ightleftharpoons 3 hydroxy L kynurenine + NADP+ + H2OThe 4 substrates of this enzyme are L… …   Wikipedia

  • Kynurenine — Chembox new ImageFile=Kynurenine.svg ImageSize= IUPACName=2 amino 4 (2 aminophenyl) 4 oxo butanoic acid OtherNames= Section1= Chembox Identifiers CASNo=343 65 7 PubChem=846 SMILES=C1=CC=C(C(=C1)C(=O)CC(C(=O)O)N)N MeSHName=Kynurenine Section2=… …   Wikipedia

  • kynurenine 3-hydroxylase — kyn·ure·nine 3 hy·drox·y·lase (kīn uґrə nēn″ hi drokґsĭ lās) kynurenine 3 monooxygenase …   Medical dictionary

  • kynurenine — A product of the metabolism of l tryptophan, excreted in the urine in small amounts; elevated in cases of vitamin B6 deficiency. k. formamidase SYN: formamidase. k. 3 hydroxylase SYN: k. 3 monooxygenase. k. 3 monooxygenase an enzyme catalyzing… …   Medical dictionary

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • KMO (gene) — Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase), also known as KMO, is a human gene.cite web | title = Entrez Gene: KMO kynurenine 3 monooxygenase (kynurenine 3 hydroxylase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • 343-65-7 — Kynurenine Kynurenine Général Nom IUPAC 2 amino 4 (2 aminophenyl) 4 oxo butanoic acid …   Wikipédia en Français

  • C10H12N2O3 — Kynurenine Kynurenine Général Nom IUPAC 2 amino 4 (2 aminophenyl) 4 oxo butanoic acid …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”