Kynurenine 7,8-hydroxylase

Kynurenine 7,8-hydroxylase

In enzymology, a kynurenine 7,8-hydroxylase (EC number|1.14.99.2) is an enzyme that catalyzes the chemical reaction

:kynurenate + AH2 + O2 ightleftharpoons 7,8-dihydro-7,8-dihydroxykynurenate + A

The 3 substrates of this enzyme are kynurenate, AH2, and O2, whereas its two products are 7,8-dihydro-7,8-dihydroxykynurenate and A.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating). Other names in common use include kynurenic acid hydroxylase, kynurenic hydroxylase, and kynurenate 7,8-hydroxylase. This enzyme participates in tryptophan metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9029-63-4."

Gene Ontology (GO) codes


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