Glucose-6-phosphate isomerase
- Glucose-6-phosphate isomerase
Protbox
Name =Glucose phosphate isomerase
Photo=Glucose-6-phosphate isomerase 1GZV wpmp.pngCaption={! align="center" border="0"! Enzyme! Glucose-6-phosphate isomerase!-! PDB Code!-! Organism! Pig!-! Tissue! Muscle!-! Complexed molecules! 5-phosphoarabinoate
HGNCid = 4458
Symbol = GPI
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Chromosome = 19
Arm = q
Band = 13.1
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EntrezGene = 2821
OMIM = 172400
RefSeq = NM_000175
UniProt = P06744
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ECnumber = 5.3.1.9
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Glucose-6-phosphate isomerase, or phosphoglucose isomerase, is an enzyme (EC number|5.3.1.9) that catalyzes the conversion of glucose-6-phosphate into fructose-6-phosphate in the second step of glycolysis. An unrelated enzyme, D-xylose isomerase (EC number|5.3.1.5) catalyzes the isomerization of glucose to fructose, and is sometimes called "glucose isomerase".
The human variant of this enzyme is encoded by the GPI gene.
In glycolysis
Enzymatic Reaction
foward_enzyme=Phosphoglucose isomerase
reverse_enzyme=Phosphoglucose isomerase
substrate=α-D-Glucose 6-phosphate
product=β-D-Fructose 6-phosphate
reaction_direction_(foward/reversible/reverse)=reversible
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As a glucose isomerase
Enzymatic Reaction
foward_enzyme=Phosphoglucose isomerase
reverse_enzyme=Phosphoglucose isomerase
substrate=D-Glucose
product=D-Fructose
reaction_direction_(foward/reversible/reverse)=reversible
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Other functions
There is evidence that phosphoglucose isomerase acts as a molecular messenger. It is produced and secreted by white blood cells, and acts to regulate the growth of several different cell types.
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Look at other dictionaries:
Glucose-6-phosphate isomérase — N° EC … Wikipédia en Français
glucose-6-phosphate isomerase — glu·cose 6 phos·phate isom·er·ase (glooґkos fosґfāt i somґər ās) [EC 5.3.1.9] an enzyme of the isomerase class that catalyzes the interconversion glucose 6 phosphate = fructose 6 phosphate. The forward reaction is a step in the… … Medical dictionary
Glucose-6-phosphat-Isomerase — Oberflächenmodell des G6PI Dimer, rechts eine Untereinheit als Cartoon, nach … Deutsch Wikipedia
Glucose-6-Phosphat-Isomerase — Kalottenmodell der GPI vom Wildkaninchen (Oryctolagus cuniculus) mit Su … Deutsch Wikipedia
Glucose-6-phosphate — Glucose 6 phosphate … Wikipédia en Français
glucose phosphate isomerase — glucose phosphate isomerase. См. глюкозофосфатизомераза. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Glucose-6-phosphate — Chembox new ImageFileL1=Glucose 6 phosphate skeletal.png ImageFileR1=Beta D glucose 6 phosphate 3D balls.png ImageSize= IUPACName=(3,4,5,6 tetrahydroxytetrahydropyran 2 yl) methoxyphosphonic acid OtherNames= Section1= Chembox Identifiers CASNo=56 … Wikipedia
glucose-phosphate isomerase — An enzyme that catalyzes the reversible interconversion of d fructose 6 phosphate and d glucose 6 phosphate; a part of glycolysis and gluconeogenesis; glucosephosphate isomerase deficiency is an inherited disorder resulting in liver … Medical dictionary
Glucose-6-phosphate 1-epimerase — In enzymology, a glucose 6 phosphate 1 epimerase (EC number|5.1.3.15) is an enzyme that catalyzes the chemical reaction:alpha D glucose 6 phosphate ightleftharpoons beta D glucose 6 phosphateHence, this enzyme has one substrate, alpha D glucose 6 … Wikipedia
glucose-1-phosphate phosphodismutase — A phosphotransferase catalyzing the reversible transfer of a phosphate residue from one d glucose 1 phosphate to another, yielding d glucose 1,6 bisphosphate and d glucose. This enzyme provides a crucial intermediate needed for glucose phosphate… … Medical dictionary
