- Chondropathy
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Chondropathy Classification and external resources ICD-10 M91-M94 ICD-9 732-733 MeSH D002357 In medicine, Chondropathy refers to a disease of the cartilage. It is frequently divided into 5 grades, with 0-2 defined as normal, and 3-4 defined as diseased.
Cartilage diseases
Some common diseases affecting/involving the cartilage are listed below.
- Osteoarthritis: The cartilage covering bones (articular cartilage) is thinned, eventually completely worn out, resulting in a "bone against bone" joint, resulting in pain and reduced mobility. Osteoarthritis is very common, affects the joints exposed to high stress and is therefore considered the result of "wear and tear" rather than a true disease. It is treated by Arthroplasty, the replacement of the joint by a synthetic joint made of titanium and teflon. Chondroitin sulfate, a monomer of the polysaccharide portion of proteoglycan, has been shown to reduce the symptoms of osteoarthritis, possibly by increasing the synthesis of the extracellular matrix.
- Achondroplasia: Reduced proliferation of chondrocytes in the epiphyseal plate of long bones during infancy and childhood, resulting in dwarfism.
- Costochondritis: Inflammation of cartilage in the ribs, causing chest pain.
- Spinal disc herniation: Asymmetrical compression of an intervertebral disc ruptures the sac-like disc, causing a herniation of its soft content. The hernia compresses the adjacent nerves and causes back pain.
- Relapsing polychondritis: a destruction, probably autoimmune, of cartilage, especially of the nose and ears, causing disfiguration. Death occurs by suffocation as the larynx loses its rigidity and collapses.
- Cartilage tumors
Repairing articular cartilage damage
Though articular cartilage damage is not life threatening, it does strongly affect the quality of life. Articular cartilage damage is often the cause of severe pain, swellings, strong barries to mobility and severe restrictions to the patient's activities. Over the last decades, however, surgeons and biotech ventures have elaborated promising procedures that contribute to articular cartilage repair. These procedures do not, however, treat osteoarthritis.
External links
- The KNEEguru - educational site packed with knee content with sections on articular cartilage problems
- [1] American Orthopaedic Society for Sports Medicine
- [2] The Steadman-Hawkins Clinic
Pathology: Medical conditions and ICD code (Disease / Disorder / Illness, Syndrome / Sequence, Symptom / Sign, Injury, etc.) (A/B, 001–139) Infectious disease/Infection: Bacterial disease (G+, G-) · Virus disease · Parasitic disease (Protozoan infection, Helminthiasis, Ectoparasitic infestation) · Mycosis · Zoonosis(C/D,
140–239 &
279–289)Cancer (C00–D48, 140–239)Myeloid hematologic (D50–D77, 280–289)(E, 240–278) (F, 290–319) (G, 320–359) (H, 360–389) (I, 390–459) (J, 460–519) (K, 520–579) Stomatognathic disease (Tooth disease) · Digestive disease (Esophageal, Stomach, Enteropathy, Liver, Pancreatic)(L, 680–709) (M, 710–739) (N, 580–629) Urologic disease (Nephropathy, Urinary bladder disease) · Male genital disease · Breast disease · Female genital disease(O, 630–679) (P, 760–779) (Q, 740–759) (R, 780–799) (S/T, 800–999) Osteochondropathy (M80–M94, 730–733) Osteopathies endocrine bone disease: Osteitis fibrosa cystica (Brown tumor)infectious bone disease: Osteomyelitis (Sequestrum, Involucrum) · Sesamoiditis · Brodie abscess · PeriostitisBone density
and structureDensity / metabolic bone diseaseContinuity of boneOtherFibrous dysplasia (Monostotic, Polyostotic) · Skeletal fluorosis · bone cyst (Aneurysmal bone cyst) · Hyperostosis (Infantile cortical hyperostosis) · Osteosclerosis (Melorheostosis)OtherChondropathies OtherBoth lower limb: hip (Legg–Calvé–Perthes syndrome) · tibia (Osgood-Schlatter disease, Blount's disease) · foot (Köhler disease, Sever's disease)Categories:- Chondropathies
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