- Liver disease
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MeshID = D008107Liver disease is a broad term describing any number of
disease s affecting theliver . Many are accompanied byjaundice caused by increased levels ofbilirubin in the system. The bilirubin results from the breakup of thehemoglobin of deadred blood cell s; normally, the liver removes bilirubin from the blood and excretes it through bile.
*Hepatitis , inflammation of the liver, caused mainly by variousvirus es but also by some poisons, autoimmunity or hereditary conditions.
*Cirrhosis is the formation of fibrous tissue in the liver, replacing dead liver cells. The death of the liver cells can for example be caused by viral hepatitis,alcoholism or contact with other liver-toxic chemicals.
*Haemochromatosis , a hereditary disease causing the accumulation ofiron in the body, eventually leading to liver damage.
*Cancer of the liver (primaryhepatocellular carcinoma orcholangiocarcinoma and metastatic cancers, usually from other parts of thegastrointestinal tract ).
*Wilson's disease , ahereditary disease which causes the body to retaincopper .
*Primary sclerosing cholangitis , an inflammatory disease of thebile duct , likely autoimmune in nature.
*Primary biliary cirrhosis , autoimmune disease of small bile ducts.
*Budd-Chiari syndrome , obstruction of the hepatic vein.
*Gilbert's syndrome , a genetic disorder ofbilirubin metabolism, found in about 5% of the population.
*Glycogen storage disease type II , the build-up of glycogen causes progressive muscle weakness (myopathy) throughout the body and affects various body tissues, particularly in the heart, skeletal muscles, liver and nervous system.There are also many pediatric liver disease, including
biliary atresia ,alpha-1 antitrypsin deficiency ,alagille syndrome , andprogressive familial intrahepatic cholestasis , to name but a few.A number of
liver function tests are available to test the proper function of the liver. These test for the presence of enzymes in blood that are normally most abundant in liver tissue, metabolites or products.ymptoms of a diseased liver
The external signs include a coated tongue, bad breath, skin rashes, itchy skin, excessive sweating, offensive body odour, dark circles under the eyes, red swollen and itchy eyes, acne
rosacea , brownish spots and blemishes on the skin, flushed facial appearance or excessive facial blood vessels. [ [http://www.liverdoctor.com/index.php?page=symptoms Dr Sandra Cabot - The Liver Doctor] ] Other symptoms include jaundice, dark urine, pale stool, bone loss, easy bleeding, itching, small, spider-like blood vessels visible in the skin, enlarged spleen, fluid in the abdominal cavity, chills, pain from the biliary tract or pancrea, and an enlarged gallbladder. [ [http://www.umm.edu/liver/common.htm University of Maryland - Symptoms of Liver Disease] ]The symptoms related to liver dysfunction include both physical signs and a variety of symptoms related to digestive problems, blood sugar problems, immune disorders, abnormal absorption of fats, and metabolism problems. [ [http://www.liverdoctor.com/index.php?page=symptoms Dr Sandra Cabot - The Liver Doctor] ]
The malabsorption of fats may lead to symptoms that include indigestion, reflux, hemorrhoids, gall stones, intolerance to fatty foods, intolerance to alcohol, nausea and vomiting attacks, abdominal bloating, and constipation.
Nervous system disorders include depression, mood changes, especially anger and irritability, poor concentration and "
foggy brain ," overheating of the body, especially the face and torso, and recurrent headaches (including migraine) associated with nausea.The blood sugar problems include a craving for sugar, hypoglycaemia and unstable blood sugar levels, and the onset of
type 2 diabetes .Abnormalities in the level of fats in the blood stream include elevated LDL cholesterol, reduced HDL cholesterol, elevated triglycerides, clogged arteries leading to high blood pressure heart attacks and strokes, build up of fat in other body organs (fatty degeneration of organs), lumps of fat in the skin (lipomas and other fatty tumors), excessive weight gain (which may lead to obesity), inability to lose weight even while dieting, sluggish metabolism, protuberant abdomen (pot belly), cellulite, fatty liver, and a roll of fat around the upper abdomen (liver roll). [ [http://www.liverdoctor.com/index.php?page=symptoms Dr Sandra Cabot - The Liver Doctor] ]
Treatment of liver diseases
Natural medicine
- The most commonly used herbs for liver problems include
Milk Thistle ,Sho-saiko-to ,Dandelion Root,Licorice Root, andChicory root. [Prescription for Natural Cures, Dr. James F. Balch, 2004, pages 302-304] -Milk Thistle [ [http://www.mskcc.org/mskcc/html/69303.cfm Milk Thistle: Memorial Sloan-Kettering Cancer Center] ] is the best studied herb for hepatitis, and has been shown to help protect and regenerate liver cells. [Prescription for Natural Cures, Dr. James F. Balch, 2004, page 615]References
External links
* [http://www.eliver.org Liver disease types, symptoms and detailed information]
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