- Dressler's syndrome
Dressler's syndrome Classification and external resources ICD-10 I24.1 ICD-9 411.0 DiseasesDB 3947
Dressler's syndrome is a secondary form of pericarditis that occurs in the setting of injury to the heart or the pericardium (the outer lining of the heart). It consists of a triad of features, fever, pleuritic pain and pericardial effusion.
Dressler's syndrome is also known as postmyocardial infarction syndrome and the term is sometimes used to refer to post-pericardiotomy pericarditis.
Dressler's syndrome is largely a self limiting disease that very rarely leads to pericardial tamponade. The syndrome consists of a persistent low-grade fever, chest pain (usually pleuritic in nature), a pericardial friction rub, and /or a pericardial effusion. The symptoms tend to occur 2 weeks post myocardial infarction, but can be delayed for a few months after infarction. It tends to subside in a few days. An elevated ESR is an objective laboratory finding.
It is believed to result from an autoimmune inflammatory reaction to myocardial neo-antigens formed as a result of the MI. A similar pericarditis can be associated with any pericardiotomy or trauma to the percardium or heart surgery.
In the setting of myocardial infarction, Dressler's syndrome occurs in about 7% of cases, and typically occurs 2-3 weeks post-myocardial infarction. Dressler's syndome is also known as post-myocardial infarction syndrome, post-cardiac injury syndrome and postpericardiotomy syndrome. Dressler's syndrome needs to be differentiated from pulmonary embolism, another identifiable cause of pleuritic (and non-pleuritic) chest pain in people who have been hospitalized and/or undergone surgical procedures within the preceding weeks.
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- ^ Dressler W (January 1959). "The post-myocardial-infarction syndrome: a report on forty-four cases". AMA Arch Intern Med 103 (1): 28–42. PMID 13605300.
- ^ synd/3982 at Who Named It?
- ^ L. A. Dressler. Ein Fall von intermittirender Albuminurie und Chromaturie. Archiv für pathologische Anatomie und Physiologie und für klinische Medicin, 1854, 6: 264-266.
- ^ Krainin F, Flessas A, Spodick D (1984). "Infarction-associated pericarditis. Rarity of diagnostic electrocardiogram". N Engl J Med 311 (19): 1211–4. doi:10.1056/NEJM198411083111903. PMID 6493274.
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Cardiovascular disease: heart disease · Circulatory system pathology (I00–I52, 390–429) IschaemicActive ischemia LayersValves Conduction/
arrhythmiaPremature contractionWolff-Parkinson-White · Lown-Ganong-LevineFlutter/fibrillationPacemakerOther/ungrouped
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