Myocardial stunning

Myocardial stunning
Myocardial stunning
Classification and external resources
MeSH D017682

Myocardial stunning is the reversible reduction of function of heart contraction[1] after reperfusion not accounted for by tissue damage or reduced blood flow.[2]

After total ischemia occurs, the myocardium switches immediately form aerobic glycolysis to anaerobic glycolysis resulting in the reduced ability to produce high energy phosphates such as ATP and Creatinine Phosphate. At this point, the lack of the energy and lactate accumulation results in cessation of contraction within 60 seconds of ischemia (i.e. Vessel Occlusion). Subsequent to this is a period of "myocardial stunning," in which reversible ischemic damage is taking place. At approximately 30 minutes after the onset of total ischemia the damage becomes irreversible, thereby ending the phase of myocardial stunning.


  1. ^ MeSH Myocardial+Stunning
  2. ^ Grund F (February 2001). "[Three cardiac mysteries--stunning, hibernation and ischemic preconditioning]" (in Norwegian). Tidsskr. Nor. Laegeforen. 121 (4): 440–4. PMID 11255859. 

External links

Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • myocardial stunning — temporarily impaired myocardial function, resulting from a brief episode of ischemia, that persists for some period after reperfusion. Cf. myocardial hibernation …   Medical dictionary

  • Myocardial rupture — Classification and external resources ICD 10 I23.3 I23.5, S26.8 eMedicine …   Wikipedia

  • Myocardial scarring — is fibrous tissue that replaces normal tissue destroyed by injury or disease pertaining to the muscular tissue of the heart. Myocardial scarring occurs in myocardial infarction, and also results from the surgical repair of congenital heart… …   Wikipedia

  • Myocardial ischemia — is an imbalance between myocardial oxygen supply and demand. Left untreated, it results in angina pectoris, myocardial stunning, myocardial hibernation, ischemic preconditioning, postconditioning, or under the most severe instances, acute… …   Wikipedia

  • Myocardial infarction — Heart attack redirects here. For other uses, see Heart attack (disambiguation). Myocardial infarction Classification and external resources Diagram of a myocardial infarction (2) of the tip of the anterior wall of the heart (an apical infarct)… …   Wikipedia

  • Myocardial infarction complications — Main article: Myocardial infarction Myocardial infarction complications may occur immediately following a heart attack (in the acute phase), or may need time to develop (a chronic problem). After an infarction, an obvious complication is a second …   Wikipedia

  • myocardial hibernation — chronic but potentially reversible cardiac dysfunction caused by chronic myocardial ischemia, persisting at least until blood flow is restored. Cf. myocardial stunning …   Medical dictionary

  • Takotsubo cardiomyopathy — Infobox Disease Name = PAGENAME Caption = Schematic representation of Takotsubo cardiomyopathy (A) compared to the situation in a normal person (B). DiseasesDB = 33976 ICD10 = ICD9 = ICD9|429.83 ICDO = OMIM = MedlinePlus = eMedicineSubj =… …   Wikipedia

  • ICD-10 Chapter IX: Diseases of the circulatory system — International Statistical Classification of Diseases and Related Health Problems 10th Revision Chapter Blocks Title I A00–B99 Certain infectious and parasitic diseases II C00–D48 Neoplasms III D50–D89 Diseases of the blood and blood forming… …   Wikipedia

  • Coronary artery disease — Classification and external resources Micrograph of a coronary artery with the most common form of coronary artery disease (atherosclerosis) and marked luminal narrowing. Masson s trichrome …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”