Libman-Sacks endocarditis
- Libman-Sacks endocarditis
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eMedicineSubj = med
eMedicineTopic = 1295
MeshID = D008180
Libman-Sacks endocarditis is a form of nonbacterial endocarditis that is seen in systemic lupus erythematosus. It is the most common cardiac manifestation of lupus.
It was first described by Drs. Emanuel Libman and Benjamin Sacks at Mount Sinai Hospital in New York City in 1924. [Libman E, Sacks B: A hitherto undescribed form of valvular and mural endocarditis. Arch Intern Med 1924; 33: 701-37.] [ [http://www.patient.co.uk/showdoc/40024946/ Patient.co.uk: Libman-Sacks Endocarditis] Retrieved 2008-08-11] The association between Libman-Sacks endocarditis and Antiphospholipid syndrome was first noted in 1985.
Presentation
The vegetations are small and formed from strands of fibrin, neutrophils, lymphocytes, and histiocytes. The mitral valve is typically affected, and the vegetations occur on the ventricular and atrial surface of the valve. Libman-Sacks lesions rarely produce significant valve dysfunction and the lesions only rarely embolize.
Pathology
The pathology is the same as nonbacterial thrombotic endocarditis except focal necrosis (hematoxylin bodies) can be found only in Libman-Sacks endocarditis.
References
Wikimedia Foundation.
2010.
Look at other dictionaries:
Libman-Sacks endocarditis — Lib·man Sacks endocarditis lib mən saks n a noninfectious form of verrucous endocarditis associated with systemic lupus erythematosus called also Libman Sacks disease, Libman Sacks syndrome Libman Emanuel (1872 1946), and Sacks Benjamin (1896… … Medical dictionary
Libman-Sacks endocarditis (disease) vegetations — Lib·man Sacks endocarditis (disease), vegetations (libґmən saksґ) [Emanuel Libman, American physician, 1872–1946; Benjamin Sacks, American physician, 1873–1939] see under endocarditis and vegetation … Medical dictionary
Libman-Sacks endocarditis — noun a form of non bacterial endocarditis seen in systemic lupus erythematosus (SLE), and is its most common cardiac presentation … Wiktionary
Libman-Sacks vegetations — the vegetations seen on cardiac valves in Libman Sacks endocarditis … Medical dictionary
Endocarditis de Libman-Sacks — Saltar a navegación, búsqueda Endocarditis de Libman Sacks Clasificación y recursos externos Aviso médico CIE 10 … Wikipedia Español
endocarditis de Libman-Sacks — proceso patológico y la manifestación más frecuente del lupus eritematoso, caracterizada por lesiones verrucosas que se desarrollan cerca de las válvulas cardíacas, aunque rara vez afectan a su funcionamiento imagen patológica [véase… … Diccionario médico
Libman-Sacks disease — see under endocarditis … Medical dictionary
síndrome de KAPOSI-BESNIER-LIBMAN-SACKS — estadio final del lupus sistémico eritematoso, caracterizado por una endocarditis atípical, verrucosa, no bacteriana, valvular y mural endocarditis. Es la manifestación visceral de un lupus eritematoso diseminado sistémico que presenta murmullos… … Diccionario médico
síndrome de LIBMAN-SACKS — estadio final del lupus sistémico eritematoso, caracterizado por una endocarditis atípical, verrucosa, no bacteriana, valvular y mural endocarditis. Es la manifestación visceral de un lupus eritematoso diseminado sistémico que presenta murmullos… … Diccionario médico
Endocarditis — eMedicine2|ped|2511 MeshID = D004696 Endocarditis is an inflammation of the inner layer of the heart, the endocardium. It usually involves the heart valves (native or prosthetic valves). Other structures which may be involved include the… … Wikipedia
