Nonbacterial thrombotic endocarditis

Nonbacterial thrombotic endocarditis
Nonbacterial thrombotic endocarditis
Classification and external resources
DiseasesDB 29250

Marantic endocarditis, also known as non-bacterial thrombotic endocarditis (NBTE), is the deposition of small sterile vegetations on valve leaflets.

The previous term for nonbacterial thrombotic endocarditis (NBTE) was marantic endocarditis, from the Greek marantikos, meaning “wasting away.”[1]

The term "Marantic endocarditis" is still sometimes used to emphasize the association with a wasting state[2] such as cancer.[3]

Contents

Risk factors

Marantic vegetations are often associated with previous rheumatic fever.

Other risk factors include:

Valve predilection

The disease affects the valves with the following predilection:

mitral valve > aortic valve > tricuspid valve > pulmonary valve.

Presentation

Grossly, vegetations form along lines of valve closure and are generally symmetric with a smooth or verrucoid (warty) texture. Histologically, lesions are composed of fibrin[4] (eosinophilic) and platelets but, unlike bacterial etiologies, contain little evidence of PMNs, microorganisms or inflammation.

Diagnosis

Due to the non-invasive nature of NBTE, clinical examination may or may not reveal a new murmur.

An embolic stroke may be the first feature to suggest the diagnosis of NBTE. An echocardiograph may be used to further assess for valvular lesions.

References

  1. ^ "eMedicine - Neurological Sequelae of Infectious Endocarditis : Article by Milind J Kothari". http://www.emedicine.com/neuro/topic264.htm. Retrieved 2008-03-23. 
  2. ^ "Noninfective Endocarditis: Endocarditis: Merck Manual Professional". http://www.merck.com/mmpe/sec07/ch077/ch077c.html#sec07-ch077-ch077b-1476. Retrieved 2008-12-22. 
  3. ^ "Definition: marantic endocarditis from Online Medical Dictionary". http://cancerweb.ncl.ac.uk/cgi-bin/omd?marantic+endocarditis. Retrieved 2008-12-22. 
  4. ^ "nonbacterial thrombotic endocarditis" at Dorland's Medical Dictionary



Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • nonbacterial thrombotic endocarditis — (NBTE) endocarditis usually occurring in chronic debilitating disease, particularly malignancy; it is characterized by noninfected vegetations composed of fibrin and other blood elements, generally located on the line of closure of the mitral and …   Medical dictionary

  • endocarditis — endocarditic /en doh kahr dit ik/, adj. /en doh kahr duy tis/, n. Pathol. inflammation of the endocardium. [1830 40; < NL; see ENDO , CARDITIS] * * * Inflammation of the heart lining (endocardium), in association with a noninfectious disease (e.g …   Universalium

  • endocarditis — Inflammation of the endocardium. SYN: encarditis. abacterial thrombotic e. SYN: nonbacterial thrombotic e.. acute bacterial e. a type of severe bacterial e. caused by pyogenic organisms such as hemolytic …   Medical dictionary

  • Endocarditis — eMedicine2|ped|2511 MeshID = D004696 Endocarditis is an inflammation of the inner layer of the heart, the endocardium. It usually involves the heart valves (native or prosthetic valves). Other structures which may be involved include the… …   Wikipedia

  • Libman-Sacks endocarditis — ICDO = OMIM = MedlinePlus = eMedicineSubj = med eMedicineTopic = 1295 MeshID = D008180 Libman Sacks endocarditis is a form of nonbacterial endocarditis that is seen in systemic lupus erythematosus. It is the most common cardiac manifestation of… …   Wikipedia

  • Libman-Sacks endocarditis — Lib·man Sacks endocarditis lib mən saks n a noninfectious form of verrucous endocarditis associated with systemic lupus erythematosus called also Libman Sacks disease, Libman Sacks syndrome Libman Emanuel (1872 1946), and Sacks Benjamin (1896… …   Medical dictionary

  • marantic endocarditis — nonbacterial thrombotic e …   Medical dictionary

  • NBTE — • nonbacterial thrombotic endocarditis …   Dictionary of medical acronyms & abbreviations

  • NBTE — nonbacterial thrombotic endocarditis * * * nonbacterial thrombotic endocarditis …   Medical dictionary

  • NBTE — Nonbacterial Thrombotic Endocarditis (Medical) …   Abbreviations dictionary

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”