Co-dydramol

Co-dydramol
Co-dydramol
Combination of
Dihydrocodeine Opioid analgesic
Paracetamol Non-opioid analgesic
Clinical data
Pregnancy cat.  ?
Legal status POM (UK)
Routes Oral
Identifiers
ATC code  ?
ChemSpider 21106280 YesY
 YesY(what is this?)  (verify)

Co-dydramol (BAN) is a non-proprietary name used to denote a compound analgesic, a combination of dihydrocodeine tartrate and paracetamol. Co-dydramol tablets are used for the relief of moderate pain. Co-dydramol is in fact part of a series of combination drugs available in the UK and other countries including Co-codaprin (aspirin and codeine).

Contents

Formulation

All formulations of Co-dydramol contain 500 mg of paracetamol per tablet and may only be sold at a pharmacy as an over-the-counter item without prescription (a P medicine) if containing less than 7.5 mg of dihydrocodeine per tablet. Higher strengths are prescription only medicines. There are no GSL formulations of co-dydramol, as it is a Schedule 5 Controlled Drug. Four strengths of dihydrocodeine tartrate in each tablet are available:

  • 7.46 mg dihydrocodeine in the brand Paramol.
  • 10 mg dihydrocodeine, BAN of Co-dydramol 10/500, this is also the preparation to be dispensed if no strength is specified on a prescription.
  • 20 mg dihydrocodeine, BAN of Co-dydramol 20/500 (branded product Remedeine).
  • 30 mg dihydrocodeine, BAN of Co-dydramol 30/500 (branded product Remedeine forte).

Possible Side Effects

  • Allergic reactions - skin rash or itchy skin, difficulty breathing, increased sweating, redness or flushed face, mucosal lesions (such as mouth ulcers), drug fever.
  • Abdominal pain - may be caused by spasm of the bile ducts and inflammation of the liver or pancreas.
  • Gastrointestinal system - stomach irritation (mild stomach pain, heartburn and feeling sick), constipation, feeling or being sick, loss of appetite, dry mouth, difficulty in passage of food through the gut.
  • Blood - anaemia, changes in numbers and types of blood cells, nose bleeds, increased risk of infection, bruising.
  • Urinary system - pain or difficulty in passing urine.
  • Nervous system - confusion, drowsiness, dizziness, 'spinning' sensation, mood changes, depression, hallucinations, restlessness, excitation, fits, increased pressure in the skull (painful eyes, changes in vision), headache, difficulty sleeping, nightmares, reduced alertness. Tolerance or dependence.
  • Eyes - blurred or double vision, extremely small pupils.
  • Other - trembling, unusual tiredness or weakness, malaise, low body temperature, breathing difficulties, muscle stiffness, changes in sex drive.

References

  • British National Formulary 2004
  • Merck Index 13th Edition
  • Oxford textbook of clinical pharmacology Second Edition (09. October 1992)
  • Martindale: The complete drug reference 35th Edition (2007)
  • Goodman & Gilman's The Pharmacological Basis of Therapeutics, 11th Edition
  • Information on the packaging leflet

See also

External links


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Look at other dictionaries:

  • co-dydramol — n.; see dihydrocodeine …   The new mediacal dictionary

  • Dihydrocodeine — Systematic (IUPAC) name 4,5 alpha epoxy 3 methoxy 17 methylmorphinan 6 ol Clinical data AHFS/Drugs.com …   Wikipedia

  • Paracetamol — Acetaminophen Systematic (IUPAC) name …   Wikipedia

  • British Approved Name — A British Approved Name (BAN) is the official non proprietary or generic name given to a pharmaceutical substance, as defined in the British Pharmacopoeia (BP). The BAN is also the official name used in many countries across the world, especially …   Wikipedia

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  • Co-codaprin — Combination of Aspirin Non opioid analgesic, NSAID Codeine phosphate Opioid analgesic Clinical data AHFS/Drugs.com …   Wikipedia

  • dihydrocodeine — n. an opioid analgesic used to relieve moderate pain (see opiate). It is administered by mouth or injection and sometimes causes nausea, dizziness, and constipation. Dependence of the morphine type can also occur, but this is rare. Dihydrocodeine …   The new mediacal dictionary

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