Osthol

Osthol: Osthol

IUPAC name

7-methoxy-8-(3-methylbut-2-enyl)-2-chromenone

Identifiers

CAS number 484-12-8^Y

PubChem 10228

ChemSpider 9811^Y

UNII XH1TI1759C^N

KEGG C09280^Y

ChEMBL CHEMBL52229^Y

Jmol-3D images Image 1

SMILES

O=C/2Oc1c(c(OC)ccc1\C=C\2)C\C=C(/C)C

InChI

InChI=1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3^Y
Key: MBRLOUHOWLUMFF-UHFFFAOYSA-N^Y
InChI=1/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3
Key: MBRLOUHOWLUMFF-UHFFFAOYAW

Properties

Molecular formula C₁₅H₁₆O₃

Molar mass 244.28574

N (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Infobox references

Osthol is a calcium channel blocker which is found in the plants Cnidium monnieri and Angelica pubescens.

v · d · eChannel blocker: calcium channel blockers (C08)

Selective

Dihydropyridines ("-dipine")

Amlodipine^# • Aranidipine • Azelnidipine • Barnidipine • Benidipine • Cilnidipine • Clevidipine • Darodipine • Efonidipine • Felodipine • Isradipine • Lacidipine • Manidipine • Lercanidipine • Mepirodipine • Nicardipine • Nifedipine^# • Niludipin • Nilvadipine • Nimodipine • Nisoldipine • Nitrendipine • Oxodipine • Pranidipine • Ryodipine

Phenylalkylamines ("-pamil")

Anipamil • Devapamil • Emopamil • Falipamil • Gallopamil • Norverapamil • Verapamil

1-4 Benzothiazepines ("-tiazem")

Clentiazem • Diltiazem

Non-selective
Bepridil • Fendiline • Lidoflazine • Perhexiline

Other/ungrouped
Amrinone • Anandamide • Azimilide • Bencyclane • Berbamine • Bevantolol • Canadine • Carboxyamidotriazole • Caroverine • Cinnarizine • Conotoxins • Dauricine • Dimeditiapramine • Dotarizine • Enpiperate • Eperisone • Fantofarone • Fasudil • Fenamic acid • Flunarizine • Fostedil • Gabapentin • Lamotrigine • Magnesium sulfate • Manoalide • Mibefradil^‡ • Monatepil • Naftopidil • Niguldipine • Ochratoxin A • Octylonium • Osthol • Pinaverium • Piperidine • Pregabalin • Prenylamine • Risedronic acid • Sesamodil • Stepholidine • Terodiline • Tetrahydropalmatine • Tetrandrine • Tolfenamic acid • Tranilast • TROX-1 • Ziconotide

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: VAS

anat(a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot

noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug(C2s+n/3/4/5/7/8/9)

v · coumarins

Aglycones
Aesculetin | Dicoumarol | Ferujol | Herniarin | Hymecromone | Osthol | Scopoletin | Umbelliferone

glycosides
Aesculin | Skimmin (7-O-β-D-glucopyranosylumbelliferone) | Scopolin

Furan derivatives
Furanocoumarins (Angelicin | Apterin | Bergamottin | Bergapten | Imperatorin | Marmesin | Methoxsalen | Psoralen | Trioxsalen) | Furanochromones

Monoterpene coumarin ether
Auraptene

Synthetic or drugs

Acenocoumarol | Coumatetralyl | Ensaculin | Ethyl biscoumacetate | 4-Hydroxycoumarins
| Phenprocoumon | Warfarin

Categories:
Calcium channel blockers
Coumarins
Phenol ethers
Biochemistry stubs

Osthol

IUPAC name 7-methoxy-8-(3-methylbut-2-enyl)-2-chromenone
Identifiers
CAS number	484-12-8^Y
PubChem	10228
ChemSpider	9811^Y
UNII	XH1TI1759C^N
KEGG	C09280^Y
ChEMBL	CHEMBL52229^Y
Jmol-3D images	Image 1
SMILES O=C/2Oc1c(c(OC)ccc1\C=C\2)C\C=C(/C)C
InChI InChI=1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3^Y Key: MBRLOUHOWLUMFF-UHFFFAOYSA-N^Y InChI=1/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3 Key: MBRLOUHOWLUMFF-UHFFFAOYAW
Properties
Molecular formula	C₁₅H₁₆O₃
Molar mass	244.28574
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

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Look at other dictionaries:

Coumarine — Général Nom IUPAC 1 benzopyrane 2 one … Wikipédia en Français
Остол — Общие Систематическое наименование 7 methoxy 8 (3 methylbut 2 enyl) 2 chromenone Традиционные названия Остол Химическая формула 7 methoxy 8 (3 methylbut 2 enyl) 2 chromenone Эмпирическая формула C15H16O3 … Википедия
Calcium channel blocker — A calcium channel blocker (CCB) is a chemical that disrupts the movement of calcium (Ca2+) through calcium channels.[1] CCB drugs devised to target neurons are used as antiepileptics. However, the most widespread clinical usage of calcium channel … Wikipedia
Verapamil — Systematic (IUPAC) name (RS) 2 (3,4 dimethoxyphenyl) 5 {[2 (3,4 dimethoxyphenyl)ethyl] (methyl)amino} 2 prop 2 ylpentanenitrile Clinical data Licence … Wikipedia
Amlodipine — Systematic (IUPAC) name … Wikipedia
Nifedipine — Systematic (IUPAC) name 3,5 dimethyl 2,6 dim … Wikipedia
Diltiazem — Systematic (IUPAC) name cis (+) [2 (2 dimethylaminoethyl) 5 (4 methoxyphenyl) 3 oxo 6 thia 2 azabicyclo[5.4.0]undeca 7,9, 11 trien 4 yl]ethanoate … Wikipedia
Coumarin — Not to be confused with coumadin or dicoumarol. This article is about the sweet smelling plant substance called coumarin. For the anticoagulant rodenticide poisons often called coumarins or coumadins , see 4 hydroxycoumarins. Coumarin … Wikipedia
Felodipine — Systematic (IUPAC) name 3 ethyl 5 meth … Wikipedia
Nimodipine — Systematic (IUPAC) name 3 (2 methoxyethyl) 5 propan 2 yl 2,6 dimethyl 4 (3 nitrophenyl) 1,4 dihydropyridine 3,5 dicarboxylate Clinical data … Wikipedia

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Osthol

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