- Clentiazem
-
Clentiazem acetic acid [(2S,3S)-8-chloro-5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] esterIdentifiers CAS number 111659-76-8 PubChem 57026 Jmol-3D images Image 1 - CC(=O)OC1C(SC2=C(C=CC(=C2)Cl)N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC
Properties Molecular formula C22H25ClN2O4S Molar mass 448.9629 (verify) (what is:
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references Clentiazem is a calcium channel blocker.[1]
It is a chloride derivative of diltiazem.[2]
References
- ^ Giasson S, Garceau D, Homsy W, Dumont L (October 1995). "Pharmacodynamics and pharmacokinetics of clentiazem and diltiazem in closed-chest anesthetized dogs". Cardiovasc Drugs Ther 9 (5): 685–92. doi:10.1007/BF00878551. PMID 8573551.
- ^ Dagenais F, Hollmann C, Buluran J, Cartier R (October 1995). "Clentiazem and diltiazem preserve endothelium-dependent relaxation following global rat heart ischemia". Can J Cardiol 11 (9): 816–22. PMID 7585280.
Categories:- Calcium channel blockers
- Benzothiazoles
- Lactams
- Organochlorides
- Acetate esters
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