Darodipine

Darodipine: Darodipine

IUPAC name

4-(2,1,3-benzoxadiazol-7-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester

Identifiers

CAS number 72803-02-2

PubChem 51701

ChemSpider 46790

Jmol-3D images Image 1

SMILES

O=C(OCC)\C3=C(\N\C(=C(\C(=O)OCC)C3c1cccc2nonc12)C)C

InChI

InChI=1/C19H21N3O5/c1-5-25-18(23)14-10(3)20-11(4)15(19(24)26-6-2)16(14)12-8-7-9-13-17(12)22-27-21-13/h7-9,16,20H,5-6H2,1-4H3
Key: QERUYFVNIOLCHV-UHFFFAOYAW

Properties

Molecular formula C₁₉H₂₁N₃O₅

Molar mass 371.38714

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Infobox references

Darodipine is a calcium channel blocker.

v · d · eChannel blocker: calcium channel blockers (C08)

Selective

Dihydropyridines ("-dipine")

Amlodipine^# • Aranidipine • Azelnidipine • Barnidipine • Benidipine • Cilnidipine • Clevidipine • Darodipine • Efonidipine • Felodipine • Isradipine • Lacidipine • Manidipine • Lercanidipine • Mepirodipine • Nicardipine • Nifedipine^# • Niludipin • Nilvadipine • Nimodipine • Nisoldipine • Nitrendipine • Oxodipine • Pranidipine • Ryodipine

Phenylalkylamines ("-pamil")

Anipamil • Devapamil • Emopamil • Falipamil • Gallopamil • Norverapamil • Verapamil

1-4 Benzothiazepines ("-tiazem")

Clentiazem • Diltiazem

Non-selective
Bepridil • Fendiline • Lidoflazine • Perhexiline

Other/ungrouped
Amrinone • Anandamide • Azimilide • Bencyclane • Berbamine • Bevantolol • Canadine • Carboxyamidotriazole • Caroverine • Cinnarizine • Conotoxins • Dauricine • Dimeditiapramine • Dotarizine • Enpiperate • Eperisone • Fantofarone • Fasudil • Fenamic acid • Flunarizine • Fostedil • Gabapentin • Lamotrigine • Magnesium sulfate • Manoalide • Mibefradil^‡ • Monatepil • Naftopidil • Niguldipine • Ochratoxin A • Octylonium • Osthol • Pinaverium • Piperidine • Pregabalin • Prenylamine • Risedronic acid • Sesamodil • Stepholidine • Terodiline • Tetrahydropalmatine • Tetrandrine • Tolfenamic acid • Tranilast • TROX-1 • Ziconotide

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: VAS

anat(a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot

noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug(C2s+n/3/4/5/7/8/9)

Categories:
Calcium channel blockers
Dihydropyridines
Carboxylate esters
Benzoxadiazoles
Biochemistry stubs

Darodipine

IUPAC name 4-(2,1,3-benzoxadiazol-7-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester
Identifiers
CAS number	72803-02-2
PubChem	51701
ChemSpider	46790
Jmol-3D images	Image 1
SMILES O=C(OCC)\C3=C(\N\C(=C(\C(=O)OCC)C3c1cccc2nonc12)C)C
InChI InChI=1/C19H21N3O5/c1-5-25-18(23)14-10(3)20-11(4)15(19(24)26-6-2)16(14)12-8-7-9-13-17(12)22-27-21-13/h7-9,16,20H,5-6H2,1-4H3 Key: QERUYFVNIOLCHV-UHFFFAOYAW
Properties
Molecular formula	C₁₉H₂₁N₃O₅
Molar mass	371.38714
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

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Look at other dictionaries:

Dihydropyridine — Systematic name 1,4 Dihydropyridine[1] … Wikipedia
Calcium channel blocker — A calcium channel blocker (CCB) is a chemical that disrupts the movement of calcium (Ca2+) through calcium channels.[1] CCB drugs devised to target neurons are used as antiepileptics. However, the most widespread clinical usage of calcium channel … Wikipedia
Verapamil — Systematic (IUPAC) name (RS) 2 (3,4 dimethoxyphenyl) 5 {[2 (3,4 dimethoxyphenyl)ethyl] (methyl)amino} 2 prop 2 ylpentanenitrile Clinical data Licence … Wikipedia
Amlodipine — Systematic (IUPAC) name … Wikipedia
Nifedipine — Systematic (IUPAC) name 3,5 dimethyl 2,6 dim … Wikipedia
Diltiazem — Systematic (IUPAC) name cis (+) [2 (2 dimethylaminoethyl) 5 (4 methoxyphenyl) 3 oxo 6 thia 2 azabicyclo[5.4.0]undeca 7,9, 11 trien 4 yl]ethanoate … Wikipedia
Felodipine — Systematic (IUPAC) name 3 ethyl 5 meth … Wikipedia
Nimodipine — Systematic (IUPAC) name 3 (2 methoxyethyl) 5 propan 2 yl 2,6 dimethyl 4 (3 nitrophenyl) 1,4 dihydropyridine 3,5 dicarboxylate Clinical data … Wikipedia
Nilvadipine — Systematic (IUPAC) name 5 isopropyl 3 methyl 2 cyano 6 methyl 4 (3 nitrophenyl) 1,4 dihydropyridine 3,5 dicarboxylate Clinical data AHFS/D … Wikipedia
Nicardipine — Systematic (IUPAC) name 2 [benzyl(methyl)amino]ethyl methyl 2,6 dimethyl 4 (3 nitrophenyl) 1,4 dihydropyridine 3,5 dicarboxylate Clinical data AHFS/ … Wikipedia

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Darodipine

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