Dihydropyridine

Dihydropyridine
Dihydropyridine
Systematic name
1,4-Dihydropyridine[1]
Identifiers
CAS number 3337-17-5 YesY
PubChem 104822
ChemSpider 94619 YesY
MeSH 1,4-dihydropyridine
Jmol-3D images Image 1
Properties
Molecular formula C5H7N
Molar mass 81.1158 g mol-1
Exact mass 81.057849229 g mol-1
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Dihydropyridine is a molecule based upon pyridine, and the parent of a class of molecules that have been semi-saturated with two substituents replacing one double bond. They are particularly well known in pharmacology as L-type calcium channel blockers.

Contents

Class members

The L-type calcium channel blockers include, in alphabetical order (brand names vary in different countries):

Name Image Brand name Discovered
Amlodipine
Amlodipine.png
 Norvasc, Istin
Aranidipine
Aranidipine.svg
Azelnidipine
Azelnidipine.png
Barnidipine
Barnidipine.png
Benidipine
Benidipine.png
Cilnidipine
Cilnidipine.svg
Clevidipine
Clevidipine.png
Cronidipine
Darodipine
Darodipine.png
Dexniguldipine
Efonidipine
Efonidipine.png
Elnadipine
Elgodipine
Felodipine
Felodipine.png
Flordipine
Furnidipine
Iganidipine
Isradipine
Isradipine.png
Lacidipine
Lacidipine.png
Lemildipine
Lercanidipine
Lercanidipine.svg
 Zanidip
Manidipine
Manidipine.png
Mesuldipine
Nicardipine
Nicardipine.svg
 Cardene
Nifedipine
Nifedipine.svg
 Adalat, Nifedical, Procardia
Niguldipine
Niguldipine.png
Nimodipine
Nimodipine.png
 Nimotop
Niludipine
Nilvadipine
Nilvapidine.png
Nisoldipine
Nisoldipine.svg
 Sular
Nitrendipine
Nitrendipine.svg
Olradipine
Oxodipine
Oxodipine.png
Palonidipine
Pranidipine
Pranidipine.png
Sagandipine
Sornidipine
Teludipine
Tiamdipine
Trombodipine
Watanidipine

See also

References

  1. ^ "1,4-dihydropyridine - Compound Summary". Pubchem Compound. USA: National Center for Biotechnology Information. 27 March 2005. Identification and Related Records. http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=104822&loc=ec_rcs. Retrieved 1 November 2011. 

External links

v · d · eChannel blocker: calcium channel blockers (C08)
Selective
Dihydropyridines ("-dipine")
Amlodipine# • Aranidipine • Azelnidipine • Barnidipine • Benidipine • Cilnidipine • Clevidipine • Darodipine • Efonidipine • Felodipine • Isradipine • Lacidipine • Manidipine • Lercanidipine • Mepirodipine • Nicardipine • Nifedipine# • Niludipin • Nilvadipine • Nimodipine • Nisoldipine • Nitrendipine • Oxodipine • Pranidipine • Ryodipine
Phenylalkylamines ("-pamil")
Anipamil  • Devapamil • Emopamil • Falipamil  • Gallopamil • Norverapamil  • Verapamil
1-4 Benzothiazepines ("-tiazem")
Non-selective
Bepridil • Fendiline • Lidoflazine • Perhexiline
Other/ungrouped
Amrinone  • Anandamide  • Azimilide  • Bencyclane  • Berbamine  • Bevantolol • Canadine • Carboxyamidotriazole  • Caroverine  • Cinnarizine  • Conotoxins  • Dauricine  • Dimeditiapramine • Dotarizine • Enpiperate  • Eperisone • Fantofarone  • Fasudil  • Fenamic acid  • Flunarizine  • Fostedil • Gabapentin  • Lamotrigine  • Magnesium sulfate  • Manoalide • Mibefradil‡  • Monatepil  • Naftopidil  • Niguldipine  • Ochratoxin A • Octylonium  • Osthol  • Pinaverium  • Piperidine  • Pregabalin  • Prenylamine  • Risedronic acid • Sesamodil  • Stepholidine  • Terodiline  • Tetrahydropalmatine  • Tetrandrine  • Tolfenamic acid • Tranilast  • TROX-1  • Ziconotide

M: VAS

anat(a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot

noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug(C2s+n/3/4/5/7/8/9)
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