Calcium channel

Calcium channel

A Calcium channel is an ion channel which displays selective permeabiltiy to calcium ions. It is sometimes synonymous as voltage-dependent calcium channel, [DorlandsDict|two/000019812|calcium channel] although there are also ligand-gated calcium channels.cite journal |author=Striggow F, Ehrlich BE |title=Ligand-gated calcium channels inside and out |journal=Curr. Opin. Cell Biol. |volume=8 |issue=4 |pages=490–5 |year=1996 |month=August |pmid=8791458 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0955-0674(96)80025-1]

Comparison tables

The following tables explain gating, gene, location and function of different types of calcium channels, both voltage and ligand-gated.

Voltage-gated


=Ligand-gated=

*the "receptor-operated calcium channels" (in vasoconstriction)
**P2X receptor cite book |author=Walter F., PhD. Boron |title=Medical Physiology: A Cellular And Molecular Approaoch |publisher=Elsevier/Saunders |location= |year= |pages= |isbn=1-4160-2328-3 |oclc= |doi= Page 479 ]

Pharmacology

Calcium channel blockers are used to treat hypertension.

References

External links

*


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  • calcium channel blocker — n any of a class of drugs (as verapamil) that prevent or slow the influx of calcium ions into smooth muscle cells esp. of the heart and that are used esp. to treat some forms of angina pectoris and some cardiac arrhythmias called also calcium… …   Medical dictionary

  • calcium channel blocker — n. any of a class of drugs, including nifedipine, diltiazem, and verapamil, that relax vascular and other smooth muscle tissue by preventing calcium ions from entering their cells, used to treat headaches, high blood pressure, angina pectoris,… …   Universalium

  • calcium channel blocker — n. any of a class of drugs, including nifedipine, diltiazem, and verapamil, that relax vascular and other smooth muscle tissue by preventing calcium ions from entering their cells, used to treat headaches, high blood pressure, angina pectoris,… …   English World dictionary

  • calcium-channel blocker — calcium antagonist a drug that inhibits the influx of calcium ions into cardiac and smooth muscle cells; it therefore reduces the strength of heart muscle contraction, reduces conduction of impulses in the heart, and causes vasodilatation.… …   The new mediacal dictionary

  • Calcium channel blocker — A calcium channel blocker (CCB) is a chemical that disrupts the movement of calcium (Ca2+) through calcium channels.[1] CCB drugs devised to target neurons are used as antiepileptics. However, the most widespread clinical usage of calcium channel …   Wikipedia

  • calcium channel — Membrane channel that is specific for calcium. Probably the best characterized is the voltage gated channel of the sarcoplasmic reticulum which is ryanodine sensitive. See voltage sensitive calcium channels …   Dictionary of molecular biology

  • calcium channel — a voltage gated channel, very permeable to calcium ions and slightly permeable to sodium ions, that upon activation by membrane depolarization allows calcium to flow into the cell; channels are classified into six subtypes (L, N, P, Q, R, and T)… …   Medical dictionary

  • N-type calcium channel — Calcium channel, voltage dependent, N type, alpha 1B subunit Identifiers Symbols CACNA1B; BIII; CACNL1A5; CACNN; Cav2.2 External IDs …   Wikipedia

  • P-type calcium channel — calcium channel, voltage dependent, P/Q type, alpha 1A subunit Identifiers Symbol CACNA1A Alt. symbols Cav2.1, CACNL1A4, SCA6, MHP1, MHP IUPHAR Cav2.1 …   Wikipedia

  • calcium channel blocking agent — any of a group of drugs that inhibit the entry of calcium into cells or inhibit the mobilization of calcium from intracellular stores, resulting in slowing of atrioventricular and sinoatrial conduction and relaxation of arterial smooth and… …   Medical dictionary

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