Norverapamil

Norverapamil: Norverapamil

IUPAC name

(RS)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-isopropylpentanenitrile

Identifiers

CAS number 67018-85-3

PubChem 104972

Jmol-3D images Image 1

SMILES

CC(C)C(CCCNCCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC

Properties

Molecular formula C₂₆H₃₆N₂O₄

Molar mass 440.57504

Y (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Infobox references

Norverapamil is a calcium channel blocker. It is the main active metabolite of verapamil.

v · d · eChannel blocker: calcium channel blockers (C08)

Selective

Dihydropyridines ("-dipine")

Amlodipine^# • Aranidipine • Azelnidipine • Barnidipine • Benidipine • Cilnidipine • Clevidipine • Darodipine • Efonidipine • Felodipine • Isradipine • Lacidipine • Manidipine • Lercanidipine • Mepirodipine • Nicardipine • Nifedipine^# • Niludipin • Nilvadipine • Nimodipine • Nisoldipine • Nitrendipine • Oxodipine • Pranidipine • Ryodipine

Phenylalkylamines ("-pamil")

Anipamil • Devapamil • Emopamil • Falipamil • Gallopamil • Norverapamil • Verapamil

1-4 Benzothiazepines ("-tiazem")

Clentiazem • Diltiazem

Non-selective
Bepridil • Fendiline • Lidoflazine • Perhexiline

Other/ungrouped
Amrinone • Anandamide • Azimilide • Bencyclane • Berbamine • Bevantolol • Canadine • Carboxyamidotriazole • Caroverine • Cinnarizine • Conotoxins • Dauricine • Dimeditiapramine • Dotarizine • Enpiperate • Eperisone • Fantofarone • Fasudil • Fenamic acid • Flunarizine • Fostedil • Gabapentin • Lamotrigine • Magnesium sulfate • Manoalide • Mibefradil^‡ • Monatepil • Naftopidil • Niguldipine • Ochratoxin A • Octylonium • Osthol • Pinaverium • Piperidine • Pregabalin • Prenylamine • Risedronic acid • Sesamodil • Stepholidine • Terodiline • Tetrahydropalmatine • Tetrandrine • Tolfenamic acid • Tranilast • TROX-1 • Ziconotide

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: VAS

anat(a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot

noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug(C2s+n/3/4/5/7/8/9)

Categories:
Calcium channel blockers
Phenol ethers
Nitriles
Biochemistry stubs

Norverapamil

IUPAC name (RS)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-isopropylpentanenitrile
Identifiers
CAS number	67018-85-3
PubChem	104972
Jmol-3D images	Image 1
SMILES CC(C)C(CCCNCCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC
Properties
Molecular formula	C₂₆H₃₆N₂O₄
Molar mass	440.57504
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

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Look at other dictionaries:

Verapamil — Systematic (IUPAC) name (RS) 2 (3,4 dimethoxyphenyl) 5 {[2 (3,4 dimethoxyphenyl)ethyl] (methyl)amino} 2 prop 2 ylpentanenitrile Clinical data Licence … Wikipedia
Calcium channel blocker — A calcium channel blocker (CCB) is a chemical that disrupts the movement of calcium (Ca2+) through calcium channels.[1] CCB drugs devised to target neurons are used as antiepileptics. However, the most widespread clinical usage of calcium channel … Wikipedia
Amlodipine — Systematic (IUPAC) name … Wikipedia
Nifedipine — Systematic (IUPAC) name 3,5 dimethyl 2,6 dim … Wikipedia
Diltiazem — Systematic (IUPAC) name cis (+) [2 (2 dimethylaminoethyl) 5 (4 methoxyphenyl) 3 oxo 6 thia 2 azabicyclo[5.4.0]undeca 7,9, 11 trien 4 yl]ethanoate … Wikipedia
Felodipine — Systematic (IUPAC) name 3 ethyl 5 meth … Wikipedia
Nimodipine — Systematic (IUPAC) name 3 (2 methoxyethyl) 5 propan 2 yl 2,6 dimethyl 4 (3 nitrophenyl) 1,4 dihydropyridine 3,5 dicarboxylate Clinical data … Wikipedia
Nilvadipine — Systematic (IUPAC) name 5 isopropyl 3 methyl 2 cyano 6 methyl 4 (3 nitrophenyl) 1,4 dihydropyridine 3,5 dicarboxylate Clinical data AHFS/D … Wikipedia
Nicardipine — Systematic (IUPAC) name 2 [benzyl(methyl)amino]ethyl methyl 2,6 dimethyl 4 (3 nitrophenyl) 1,4 dihydropyridine 3,5 dicarboxylate Clinical data AHFS/ … Wikipedia
Dihydropyridine — Systematic name 1,4 Dihydropyridine[1] … Wikipedia

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Norverapamil

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