O-806

O-806

Systematic (IUPAC) name
(6aR)-3-(6-bromohex-2-ynyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
ATC code	?
PubChem	CID 10549140
ChemSpider	26001356 Y
Chemical data
Formula	C22H27BrO2
Mol. mass	403.352 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C22H27BrO2/c1-15-9-10-18-17(12-15)21-19(24)13-16(8-6-4-5-7-11-23)14-20(21)25-22(18,2)3/h9,13-14,17-18,24H,5,7-8,10-12H2,1-3H3/t17-,18-/m1/s1 Y Key:QHFROVGTWNPDOW-QZTJIDSGSA-N Y
Y(what is this?)  (verify)

O-806 is a drug which is a cannabinoid derivative that is used in scientific research. It is described as a mixed agonist/antagonist at the cannabinoid receptor CB₁, meaning that it acts as an antagonist when co-administered alongside a more potent CB₁ agonist, but exhibits weak partial agonist effects when administered by itself.^[1][2]

References

1. ^ Griffin, G.; Wray, E.; Rorrer, W.; Crocker, P.; Ryan, W.; Saha, B.; Razdan, R.; Martin, B. et al. (1999). "An investigation into the structural determinants of cannabinoid receptor ligand efficacy". British journal of pharmacology 126 (7): 1575–1584. doi:10.1038/sj.bjp.0702469. PMC 1565939. PMID 10323589. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1565939.  edit
2. ^ Griffin, G.; Wray, E.; Martin, B.; Abood, M. (1999). "Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum". British journal of pharmacology 128 (3): 684–688. doi:10.1038/sj.bjp.0702806. PMC 1571656. PMID 10516649. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1571656.  edit

This cannabinoid related article is a stub. You can help Wikipedia by expanding it.v · Categories: Cannabinoids Benzochromenes Phenols Alkynes Organobromides Cannabinoid stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Valle Grande Lime Kilns (Lincoln, Rhode Island) Look at other dictionaries: 806 Naval Air Squadron — (806 NAS) was a fighter squadron in the Fleet Air Arm that existed from February 1940 to December 1960 and saw active service in Norway, the Dunkirk evacuation and the Malta Convoys. Contents 1 History 1.1 Formation 1.2 Norwegian Operations …   Wikipedia 806 Motor Lodge — (Хейстингс,Новая Зеландия) Категория отеля: 3 звездочный отель Адрес: 806 Heretaunga …   Каталог отелей 806 Gyldenia — is a minor planet orbiting the Sun.External links* [http://cfa www.harvard.edu/iau/lists/NumberedMPs.txt Discovery Circumstances: Numbered Minor Planets] …   Wikipedia 806 — Cette page concerne l année 806 du calendrier julien. Pour l année 806, voir 806. Pour la voiture, voir Peugeot 806 Années : 803 804 805  806  807 808 809 Décennies  …   Wikipédia en Français 806 год — Годы 802 · 803 · 804 · 805 806 807 · 808 · 809 · 810 Десятилетия 780 е · 790 е 800 е 810 е · …   Википедия 806 — Portal Geschichte | Portal Biografien | Aktuelle Ereignisse | Jahreskalender ◄ | 8. Jahrhundert | 9. Jahrhundert | 10. Jahrhundert | ► ◄ | 770er | 780er | 790er | 800er | 810er | 820er | 830er | ► ◄◄ | ◄ | 802 | 803 | 804 | …   Deutsch Wikipedia -806 — Années : 809 808 807   806  805 804 803 Décennies : 830 820 810   800  790 780 770 Siècles : Xe siècle av. J.‑C.  IXe siècle …   Wikipédia en Français 806 — Años: 803 804 805 – 806 – 807 808 809 Décadas: Años 770 Años 780 Años 790 – Años 800 – Años 810 Años 820 Años 830 Siglos: Siglo VIII – …   Wikipedia Español (806) Gyldénia — Asteroid (806) Gyldénia Eigenschaften des Orbits (Animation) Orbittyp Hauptgürtelasteroid Große Halbachse 3,2133 AE …   Deutsch Wikipedia (806) Gyldenia — L astéroïde (806) Gyldenia a été découvert le 18 avril 1915 par l astronome allemand Max Wolf. Sa désignation provisoire était 1915 WX. Annexes Articles connexes Liste des astéroïdes (1 1000) Ceinture d astéroïdes Lien externe (en) …   Wikipédia en Français 806 in poetry — yearbox2 in?=in poetry in2?=in literature cp=8th century c=9th century cf=10th century yp1=803 yp2=804 yp3=805 year=806 ya1=807 ya2=808 ya3=809 dp3=770s dp2=780s dp1=790s d=800s da=0 dn1=810s dn2=820s dn3=830s|Births* Tung ShanDeathsEvents …   Wikipedia 18+ © Academic, 2000-2025 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”