O-1057

O-1057

Systematic (IUPAC) name
3-(5'-cyano-1',1'-dimethylpentyl)-1-(4-N-morpholinobutyryloxy)-Δ8-tetrahydrocannabinol
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
ATC code	?
Chemical data
Formula	C32H46N2O4
Mol. mass	522.717 g/mol
SMILES	eMolecules & PubChem
Y(what is this?)  (verify)

O-1057 is an analgesic cannabinoid derivative created by Organix Inc. for use in scientific research. Unlike most cannabinoids discovered to date, it is water soluble, which gives it considerable advantages over many related cannabinoids. It has moderate affinity for both CB₁ and CB₂ receptors, with K_i values of 8.36nM at CB₁ and 7.95nM at CB₂.^[1]

See also

• AM-2232
• O-1812
• O-2694

References

1. ^ Pertwee RG, Gibson TM, Stevenson LA, Ross RA, Banner WK, Saha B, Razdan RK, Martin BR. O-1057, a potent water-soluble cannabinoid receptor agonist with antinociceptive properties. British Journal of Pharmacology. 2000 Apr;129(8):1577-84. PMID 10780961

This cannabinoid related article is a stub. You can help Wikipedia by expanding it.v · Categories: Cannabinoid stubs Cannabinoids Benzochromenes Butyrates Morpholines Nitriles Wikimedia Foundation. 2010. Игры ⚽ Поможем решить контрольную работу Mount Nishikawa Ring of Independents Look at other dictionaries: 1057 год — Годы 1053 · 1054 · 1055 · 1056 1057 1058 · 1059 · 1060 · 1061 Десятилетия 1030 е · 1040 е 1050 е 1060 е · …   Википедия 1057 — Années : 1054 1055 1056  1057  1058 1059 1060 Décennies : 1020 1030 1040  1050  1060 1070 1080 Siècles : Xe siècle  XIe  …   Wikipédia en Français 1057 — Portal Geschichte | Portal Biografien | Aktuelle Ereignisse | Jahreskalender ◄ | 10. Jahrhundert | 11. Jahrhundert | 12. Jahrhundert | ► ◄ | 1020er | 1030er | 1040er | 1050er | 1060er | 1070er | 1080er | ► ◄◄ | ◄ | 1053 | 1054 | 1055 | 1 …   Deutsch Wikipedia 1057 — ГОСТ 1057{ 88} Масла селективной очистки. Метод определения фенола и крезола. ОКС: 75.100 КГС: Б29 Методы испытаний. Упаковка. Маркировка Взамен: ГОСТ 1057 67 Действие: С 01.07.89 Примечание: переиздание 2002 в сб. Нефтепродукты. Масла. Методы… …   Справочник ГОСТов 1057 Wanda — Infobox Minor Planet name=1057 Wanda discoverer=Grigory Abramovich Shajn discovery date=August 16, 1925 category= designations=1925 QB epoch=JD 2445600.5 semimajor= perihelion=2.1881175 AU aphelion= period= speed= eccentricity=0.135 inclination=3 …   Wikipedia -1057 — Années : 1060 1059 1058   1057  1056 1055 1054 Décennies : 1080 1070 1060   1050  1040 1030 1020 Siècles : XIIe siècle av. J.‑C.  XIe siècle av. J.‑C.  …   Wikipédia en Français (1057) Wanda — Asteroid (1057) Wanda Eigenschaften des Orbits (Animation) Orbittyp Hauptgürtelasteroid Große Halbachse 2,8895 AE …   Deutsch Wikipedia 1057 in poetry — yearbox2 in?=in poetry in2?=in literature cp=10th century c=11th century cf=12th century yp1=1054 yp2=1055 yp3=1056 year=1057 ya1=1058 ya2=1059 ya3=1060 dp3=1020s dp2=1030s dp1=1040s d=1050s da=0 dn1=1060s dn2=1070s dn3=1080s|BirthsDeaths* Al Ma… …   Wikipedia 1057 — Años: 1054 1055 1056 – 1057 – 1058 1059 1060 Décadas: Años 1020 Años 1030 Años 1040 – Años 1050 – Años 1060 Años 1070 Años 1080 Siglos: Siglo X – …   Wikipedia Español 1057 — Events* King Macbeth of Scotland is killed in battle against Malcolm III of Scotland. He is succeeded as King of Scotland by his stepson Lulach. * August 2 Pope Stephen IX (sometimes referred to as Stephen X) succeeds Pope Victor II as the 154th… …   Wikipedia 1057 v. Chr. — Portal Geschichte | Portal Biografien | Aktuelle Ereignisse | Jahreskalender ◄ | 3. Jt. v. Chr. | 2. Jahrtausend v. Chr. | 1. Jt. v. Chr. | ► ◄ | 13. Jh. v. Chr. | 12. Jh. v. Chr. | 11. Jahrhundert v. Chr. | 10. Jh. v. Chr. | 9. Jh. v. Chr. | ► …   Deutsch Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”